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Related Experiment Video

Updated: Oct 18, 2025

Transcranial Direct Current Stimulation tDCS for Memory Enhancement
10:37

Transcranial Direct Current Stimulation tDCS for Memory Enhancement

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Transcranial Direct Current Stimulation (tDCS) for Memory Enhancement.

Jovana Bjekić1, Marko Živanović2, Saša R Filipović3

  • 1Institute for Medical Research, Human Neuroscience Group, University of Belgrade; jovana.bjekic@imi.bg.ac.rs.

Journal of Visualized Experiments : Jove
|October 4, 2021
PubMed
Summary

This study introduces a transcranial direct current stimulation (tDCS) protocol for memory enhancement. The non-invasive method uses targeted electrical stimulation to improve memory functions in healthy individuals and those with cognitive decline.

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Area of Science:

  • Cognitive Neuroscience
  • Neurorehabilitation
  • Neuroscience

Background:

  • Memory enhancement is a significant challenge in cognitive neuroscience and neurorehabilitation.
  • Transcranial direct current stimulation (tDCS) offers a promising non-invasive approach to improve memory functions.

Purpose of the Study:

  • To present a standardized tDCS protocol for memory enhancement applicable to healthy participants, aging research, and dementia studies.
  • To detail electrode placements and stimulation parameters for targeting the cortico-hippocampal network involved in memory.

Main Methods:

  • The protocol involves applying weak anodal current to cortical targets like the posterior parietal cortex (PPC) or dorsolateral prefrontal cortex (DLPFC).
  • A return electrode is placed extracranially (contralateral cheek).
  • An advanced method of oscillatory tDCS is also outlined, mimicking natural brain rhythms for hippocampus-dependent memory.

Main Results:

  • Single tDCS sessions (20 minutes) using specific electrode montages and current intensities (1.5-1.8 mA) demonstrated improvements in associative and working memory.
  • Illustrative results show the efficacy of the described tDCS protocol.

Conclusions:

  • The presented tDCS protocol provides a framework for memory enhancement studies.
  • Methodological considerations for designing tDCS studies on memory are discussed, emphasizing crucial steps and decisions.