Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical responses to trastuzumab deruxtecan in molecularly defined ependymoma.

NPJ precision oncology·2026
Same author

Modeling development of tertiary lymphoid structures in pulmonary tuberculosis by 3D profiling and trajectory analysis.

bioRxiv : the preprint server for biology·2026
Same author

Moving Beyond Morphology to Multiplexed Molecular Imaging as the Next Frontier in Diagnostic Pathology.

The American journal of pathology·2026
Same author

Spatial integration of protein and chromosomal states reveals early copy number changes and genotype-associated immune neighborhoods in serous ovarian cancer evolution.

Cancer discovery·2026
Same author

Live-cell Pick-Seq (LiP-Seq): Interrogating ultra-rare mantle cell lymphoma persistent cells after CART19 therapy.

Blood advances·2026
Same author

Harnessing Inflammatory Monocytes to Overcome Resistance to Anti-PD-1 Immunotherapy.

bioRxiv : the preprint server for biology·2026
Same journal

Two-phase Impulse Fluid on Particle Flow Map.

IEEE transactions on visualization and computer graphics·2026
Same journal

FGO-SLAM++: Real-time Geometry-Aware Gaussian SLAM with Continuous Opacity Field.

IEEE transactions on visualization and computer graphics·2026
Same journal

Blue Noise Dithering for Reservoir-based Spatio-temporal Importance Resampling.

IEEE transactions on visualization and computer graphics·2026
Same journal

ROS-GS: Relightable Outdoor Scenes With Gaussian Splatting.

IEEE transactions on visualization and computer graphics·2026
Same journal

MesoSplats: Texture Synthesis with Gaussian Splatting.

IEEE transactions on visualization and computer graphics·2026
Same journal

GLLA: A Unified Force-Directed Graph Layout Framework Supporting Local Adjustments.

IEEE transactions on visualization and computer graphics·2026
See all related articles

Related Experiment Video

Updated: Oct 18, 2025

Quantitative Multispectral Analysis Following Fluorescent Tissue Transplant for Visualization of Cell Origins, Types, and Interactions
11:27

Quantitative Multispectral Analysis Following Fluorescent Tissue Transplant for Visualization of Cell Origins, Types, and Interactions

Published on: September 22, 2013

9.5K

Scope2Screen: Focus+Context Techniques for Pathology Tumor Assessment in Multivariate Image Data.

Jared Jessup, Robert Krueger, Simon Warchol

    IEEE Transactions on Visualization and Computer Graphics
    |October 4, 2021
    PubMed
    Summary
    This summary is machine-generated.

    Scope2Screen is a new software system for exploring and annotating large, complex tissue images from highly multiplexed imaging. It helps pathologists visualize disease data and improve cancer diagnosis and therapy design.

    More Related Videos

    Expanding the Comprehension of the Tumor Microenvironment using Mass Spectrometry Imaging of Formalin-Fixed and Paraffin-Embedded Tissue Samples
    06:47

    Expanding the Comprehension of the Tumor Microenvironment using Mass Spectrometry Imaging of Formalin-Fixed and Paraffin-Embedded Tissue Samples

    Published on: June 29, 2022

    2.3K
    Author Spotlight: Investigating Immune Cell Dynamics in the Tumor Microenvironment — Challenges and Innovations in Cancer Prognosis
    07:32

    Author Spotlight: Investigating Immune Cell Dynamics in the Tumor Microenvironment — Challenges and Innovations in Cancer Prognosis

    Published on: April 12, 2024

    1.6K

    Related Experiment Videos

    Last Updated: Oct 18, 2025

    Quantitative Multispectral Analysis Following Fluorescent Tissue Transplant for Visualization of Cell Origins, Types, and Interactions
    11:27

    Quantitative Multispectral Analysis Following Fluorescent Tissue Transplant for Visualization of Cell Origins, Types, and Interactions

    Published on: September 22, 2013

    9.5K
    Expanding the Comprehension of the Tumor Microenvironment using Mass Spectrometry Imaging of Formalin-Fixed and Paraffin-Embedded Tissue Samples
    06:47

    Expanding the Comprehension of the Tumor Microenvironment using Mass Spectrometry Imaging of Formalin-Fixed and Paraffin-Embedded Tissue Samples

    Published on: June 29, 2022

    2.3K
    Author Spotlight: Investigating Immune Cell Dynamics in the Tumor Microenvironment — Challenges and Innovations in Cancer Prognosis
    07:32

    Author Spotlight: Investigating Immune Cell Dynamics in the Tumor Microenvironment — Challenges and Innovations in Cancer Prognosis

    Published on: April 12, 2024

    1.6K

    Area of Science:

    • Digital pathology
    • Biomedical visualization
    • Computational biology

    Background:

    • Microscopy is crucial for disease diagnosis, especially cancer.
    • Highly multiplexed tissue imaging offers deep molecular and morphological insights.
    • Visualizing and analyzing complex, high-plex tissue image data remains a challenge for digital pathology workflows.

    Purpose of the Study:

    • To develop a scalable software system, Scope2Screen, for exploring and annotating whole-slide, high-plex tissue images.
    • To address the gap in visualizing and supporting pathology workflows with multivariate image data.
    • To enable intuitive analysis of millions of cells across large image datasets.

    Main Methods:

    • Developed Scope2Screen, a scalable software system using a focus+context exploration approach.
    • Implemented interactive lensing techniques for single-cell and tissue-level analysis.
    • Integrated sliding-window search and a novel snapshot method for efficient data management and sharing.

    Main Results:

    • Scope2Screen handles large datasets (100GB images, 10^9+ pixels per channel) with millions of cells.
    • Interactive lenses provide task-specific functionality for analyzing image features, cell types, and spatial arrangements.
    • The system facilitates efficient identification, quantification, and organization of regions of interest.

    Conclusions:

    • Scope2Screen effectively supports pathology workflows by enabling intuitive visualization and analysis of high-plex tissue images.
    • The software aids in discovering cancer-relevant image features, potentially improving patient-specific therapies.
    • Validated with domain experts and applied to lung and colorectal cancer case studies.