Conservative Treatment of a Floating Mural Thrombus in the Descending Aorta

Johannes Goedemé1, Lawek Berzenji1, Simon Nicolay2

  • 1Department of Thoracic and Vascular Surgery, Antwerp University Hospital, Edegem, Belgium.

Aorta (Stamford, Conn.)
|October 4, 2021
PubMed

Insights

A floating aortic mural thrombus in a 70-year-old woman completely resolved with anticoagulation therapy. This non-invasive treatment approach proved effective for managing this rare aortic condition.

Area of Science:

  • Cardiovascular Surgery
  • Vascular Medicine
  • Thrombosis Research

Background:

  • Floating mural thrombi in the aortic arch are rare and pose a risk of embolization.
  • Diagnosis often involves advanced imaging techniques to assess thrombus characteristics and extent.
  • Management strategies vary, with a need to balance anticoagulation risks against embolic events.

Purpose of the Study:

  • To report a case of a large floating mural thrombus in the aortic arch.
  • To evaluate the efficacy of anticoagulation therapy in resolving aortic mural thrombi.
  • To highlight a successful non-operative management strategy for this condition.

Main Methods:

  • A 70-year-old female patient presented with a floating mural thrombus.
  • Diagnostic imaging confirmed thrombus location in the distal aortic arch and proximal descending aorta.
  • Treatment initiated with aspirin and low-molecular-weight heparin.

Main Results:

  • Clinical examination and imaging revealed no signs of embolization.
  • Follow-up imaging at 2 weeks and 6 months demonstrated complete resolution of the aortic mural thrombus.
  • The patient tolerated anticoagulation therapy without significant complications.

Conclusions:

  • Anticoagulation therapy with aspirin and low-molecular-weight heparin can be an effective treatment for aortic mural thrombi.
  • Non-operative management may be a viable option in select cases without evidence of embolization.
  • Complete resolution of aortic mural thrombi is achievable, reducing the risk of future embolic events.

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