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Upper gastrointestinal complaints in celiac patients at diagnosis. Association with endoscopic and histopathological

Lorete Maria da Silva Kotze1, Luiz Roberto Kotze1, Raquel Canzi Almada Souza1

  • 1Hospital de Clínicas. Universidade Federal do Paraná, Brazil.

Revista Espanola De Enfermedades Digestivas
|October 5, 2021
PubMed

Insights

This study examined upper gastrointestinal symptoms in Brazilian celiac disease (CD) patients at diagnosis. Findings were linked to endoscopic and histopathological results, offering insights into CD presentation.

Area of Science:

  • Gastroenterology
  • Internal Medicine
  • Pathology

Background:

  • Celiac disease (CD) is an autoimmune disorder affecting the small intestine.
  • Upper gastrointestinal symptoms are common in CD but their association with diagnostic findings requires further investigation.

Purpose of the Study:

  • To determine the prevalence of upper gastrointestinal symptoms in Brazilian patients diagnosed with celiac disease.
  • To correlate these symptoms with endoscopic and histopathological findings at the time of diagnosis.

Main Methods:

  • Retrospective study design.
  • Inclusion of adult patients diagnosed with celiac disease between January 2013 and December 2019.
  • Analysis of patient data, including reported symptoms, endoscopic observations, and histopathological results.

Main Results:

  • Prevalence data on specific upper gastrointestinal symptoms in the studied cohort.
  • Identification of associations between symptom presentation and endoscopic/histopathological characteristics of celiac disease.

Conclusions:

  • Upper gastrointestinal symptoms are prevalent in Brazilian celiac disease patients at diagnosis.
  • Understanding these symptom associations can aid in earlier diagnosis and management of celiac disease.

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