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Unraveling the mechanisms of IVIG immunotherapy in MIS-C

Madhusudan Ganigara1, Chetan Sharma2, Jagadeesh Bayry3

  • 1Division of Pediatric Cardiology, The University of Texas Southwestern Medical Center, Dallas, TX 75235, USA.

Cell Reports. Medicine
|October 5, 2021
PubMed

In The Journal of Clinical Investigation, Zhu et al.1 report that intravenous immunoglobulin (IVIG) targets IL-1β+ neutrophils to exert anti-inflammatory effects in multisystem inflammatory syndrome in children (MIS-C), a post-infectious inflammatory condition associated with COVID-19.

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