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Updated: Oct 18, 2025

Preparation of Acute Slices from Dorsal Hippocampus for Whole-Cell Recording and Neuronal Reconstruction in the Dentate Gyrus of Adult Mice
Published on: April 3, 2021
Abstract knowledge gets concrete in the hippocampus
1Department of Psychological and Brain Sciences and Program in Neuroscience, Indiana University Bloomington, Bloomington, IN, 47405, USA. ehnewman@iu.edu.
Abstract:
Nieh, Schottdorf, and colleagues (Nature, 595, 80-84, 2021) recently showed that hippocampal neurons of mice form a low-dimensional representation that integrates concrete and abstract task information. The reported findings confirm a long-standing prediction regarding the nature of the cognitive map and potentially offer a tantalizing glimpse of the cognitive map itself.
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