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Strategies to apply 3Rs in preclinical testing

Susana B Gorzalczany1, Angeles G Rodriguez Basso1

  • 1Universidad de Buenos Aires, Facultad de Farmacia y Bioquímica, Pharmacology Department, Buenos Aires, Argentina.

Pharmacology Research & Perspectives
|October 5, 2021
PubMed
Summary

This study explores applying the 3Rs (Replacement, Reduction, Refinement) to animal testing in preclinical research. It details methods for ethical in vivo testing, prioritizing animal welfare and reducing animal use.

Keywords:
non clinicalreductionrefinementreplacementtesting approaches

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