Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Adaptive Mechanisms in Cancer Cells02:53

Adaptive Mechanisms in Cancer Cells

6.0K
Cancer cells accumulate genetic changes at an abnormally rapid rate due to the defects in the DNA repair mechanisms. From an evolutionary perspective, such genetic instability is advantageous for cancer development. Mutant cell lines accumulate a series of beneficial mutations that contribute to their progression into cancer.
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...
6.0K
Tumor Progression02:07

Tumor Progression

6.6K
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
6.6K
Cancer Survival Analysis01:21

Cancer Survival Analysis

481
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
481
Nociception01:44

Nociception

30.9K
Nociception—the ability to feel pain—is essential for an organism’s survival and overall well-being. Noxious stimuli such as piercing pain from a sharp object, heat from an open flame, or contact with corrosive chemicals are first detected by sensory receptors, called nociceptors, located on nerve endings. Nociceptors express ion channels that convert noxious stimuli into electrical signals. When these signals reach the brain via sensory neurons, they are perceived as pain.
30.9K
mTOR Signaling and Cancer Progression03:03

mTOR Signaling and Cancer Progression

3.9K
The mammalian target of rapamycin or mTOR protein was discovered in 1994 due to its direct interaction with rapamycin. The protein gets its name from a yeast homolog called TOR. The mTOR protein complex in mammalian cells plays a major role in balancing anabolic processes such as the synthesis of proteins, lipids, and nucleotides and catabolic processes, such as autophagy in response to environmental cues, such as availability of nutrients and growth factors.
The mTOR pathway or the...
3.9K
Analgesia and Pain Management01:25

Analgesia and Pain Management

948
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
948

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same authorSame journal

Communication Breakdown in Patients With Alzheimer Disease: An Evolutionary Concept Analysis.

Professional case management·2026
Same author

Spiritual care competence and its predictors among critical and emergency nurses: a cross-sectional study of spiritual intelligence and death attitudes.

International journal of nursing studies advances·2026
Same author

Professional Autonomy and Perceived Organizational Support as Predictors of Adherence to Ethical Codes Among Emergency Nurses.

Journal of emergency nursing·2026
Same author

Associations Among Workplace Bullying, Workplace Social Capital, and Turnover Intention Among Iranian Emergency Nurses: A Cross-Sectional Study.

Journal of emergency nursing·2025
Same author

The effects of Pranayama breathing exercise on symptom burden among women with breast cancer undergoing chemotherapy: a randomized controlled trial.

BMC complementary medicine and therapies·2025
Same author

Effect of telenursing empowerment programme on self-efficacy and health status of patients with chronic obstructive pulmonary disease: randomised controlled trial.

Journal of research in nursing : JRN·2025

Related Experiment Video

Updated: Oct 18, 2025

Author Spotlight: Quantifying Pain Experience – An Illustrative Approach Using the Pain Body Diagram
09:00

Author Spotlight: Quantifying Pain Experience – An Illustrative Approach Using the Pain Body Diagram

Published on: July 7, 2023

3.9K

Cancer Pain: An Evolutionary Concept Analysis.

Marzieh Khatooni1

  • 1Marzieh Khatooni, PhD , is an assistant professor at the Faculty of Nursing & Midwifery, Qazvin University of Medical Sciences, Qazvin, Iran.

Professional Case Management
|October 5, 2021
PubMed
Summary

Cancer pain is a severe and complex issue with distinct attributes, antecedents, and consequences. Understanding these factors is crucial for effective assessment and management, differentiating it from other pain types.

More Related Videos

A Quantitative Sensory Testing Paradigm to Obtain Measures of Pain Processing in Patients Undergoing Breast Cancer Surgery
07:14

A Quantitative Sensory Testing Paradigm to Obtain Measures of Pain Processing in Patients Undergoing Breast Cancer Surgery

Published on: January 18, 2018

9.5K
An Experimental Paradigm for the Prediction of Post-Operative Pain PPOP
14:56

An Experimental Paradigm for the Prediction of Post-Operative Pain PPOP

Published on: January 27, 2010

21.5K

Related Experiment Videos

Last Updated: Oct 18, 2025

Author Spotlight: Quantifying Pain Experience – An Illustrative Approach Using the Pain Body Diagram
09:00

Author Spotlight: Quantifying Pain Experience – An Illustrative Approach Using the Pain Body Diagram

Published on: July 7, 2023

3.9K
A Quantitative Sensory Testing Paradigm to Obtain Measures of Pain Processing in Patients Undergoing Breast Cancer Surgery
07:14

A Quantitative Sensory Testing Paradigm to Obtain Measures of Pain Processing in Patients Undergoing Breast Cancer Surgery

Published on: January 18, 2018

9.5K
An Experimental Paradigm for the Prediction of Post-Operative Pain PPOP
14:56

An Experimental Paradigm for the Prediction of Post-Operative Pain PPOP

Published on: January 27, 2010

21.5K

Area of Science:

  • Nursing
  • Psychology
  • Social Sciences
  • Medicine

Background:

  • Cancer pain is a severe and common cancer-related problem.
  • Significant ambiguities exist regarding the concept and attributes of cancer pain.

Purpose of the Study:

  • To conduct a comprehensive concept analysis of cancer pain.

Main Methods:

  • Utilized Rodgers' evolutionary concept analysis method.
  • Reviewed 52 articles from nursing, psychology, social sciences, and medicine literature.
  • Employed thematic analysis for data interpretation.

Main Results:

  • Identified key attributes: origin, quality (sharp, burning, etc.), duration (acute, chronic, breakthrough), intolerability, and intensity (moderate to severe).
  • Outlined antecedents: cognitive factors, beliefs, coping, social support, finances, and cultural values.
  • Detailed consequences: physical, psychological, existential, spiritual, social, and reduced quality of life.

Conclusions:

  • Cancer pain is distinct from other pain types, necessitating specialized assessment and management strategies.
  • Findings enhance healthcare providers' understanding for improved decision-making and interventions.
  • Informs decisions regarding palliative and hospice care, crucial for case managers.