Related Experiment Video
Updated: Oct 18, 2025

Assessment of Child Anthropometry in a Large Epidemiologic Study
Published on: February 2, 2017
Obesity as a Thrombogenic and Cardiovascular Risk Factor in Children
Louise Cominato1, Ruth Rocha Franco1, Marina Ybarra1
1Instituto da Criança, São Paulo, Brazil.
Background/Aims:
Obesity leads to increased risk of thromboembolic events in adults, but few studies have addressed the relationship between obesity and thrombogenic risk during childhood. The aim of this study was to evaluate the prothrombotic state of obese children in comparison with healthy children.
Methods:
Thrombin generation, fibrinogen, and D-dimer levels, along with metabolic parameters, were measured in 72 prepubertal children, of which 47 were obese and 25 eutrophic.
Results:
A significant increase in thrombin generation, fibrinogen, and dyslipidemia was found among obese patients.
Conclusion:
A prothrombotic state develops in childhood obesity during the prepubertal phase.
Related Concept Videos
Obesity
Drug Dosing: Obese Patients
Pharmacokinetics in Obese Patients: Drug Absorption and Distribution
Coronary Artery Disease I: Introduction
Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion
Overview of Lipid Metabolism
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...

