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Toxicity of Graphene: An Update
Thiyagarajan Devasena1, Arul Prakash Francis2, Sundara Ramaprabhu3
1Centre for Nanoscience and Technology, Anna University, Chennai, India. tdevasenabio@gmail.com.
Reviews of Environmental Contamination and Toxicology
|October 6, 2021
Summary
Graphene
Area of Science:
- Nanotechnology
- Materials Science
- Environmental Science
Background:
- Graphene exhibits diverse biomedical applications, including drug delivery and diagnostics.
- Increasing environmental and human exposure to graphene necessitates understanding its toxicity.
- Graphene's unique properties present both opportunities and risks.
Purpose of the Study:
- To review current research on graphene's toxicity across various models.
- To consolidate findings on in vitro, in vivo, and environmental toxicity.
- To highlight the dual nature of graphene toxicity in biological systems.
Main Methods:
- Comprehensive literature review of graphene toxicity studies.
- Analysis of in vitro assays (cell cultures).
- Evaluation of in vivo studies (animal models) and ecotoxicity data.
Main Results:
- Graphene exhibits toxicity in in vitro and in vivo models.
- Environmental exposure poses risks to ecosystems.
- Graphene toxicity can be advantageous in targeting bacterial and cancer cells.
Conclusions:
- Graphene's biomedical potential is accompanied by significant toxicity concerns.
- Further research is crucial to mitigate risks associated with graphene exposure.
- Understanding graphene's toxicological profile is essential for safe application and environmental management.
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