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Updated: Oct 17, 2025

Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia

Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia

Published on: December 19, 2020

Organizing pneumonia-like pattern in COVID-19.

Masoomeh Raoufi¹, Shahram Kahkooei², Sara Haseli²

¹Department of Radiology, School of Medicine, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran, Tehran.

Advances in Respiratory Medicine

|October 6, 2021

Summary

This summary is machine-generated.

Organizing pneumonia (OP) patterns on initial CT scans in mild COVID-19 patients indicate a higher mortality risk. Early detection and monitoring of OP-like patterns are crucial for patient management and predicting outcomes.

Keywords:

COVID-19 computed tomography lung organizing pneumonia respiratory

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Area of Science:

Pulmonology
Radiology
Infectious Diseases

Background:

Organizing pneumonia (OP) is a radio-histologic pattern seen in response to lung injury.
OP is often observed after viral infections, including COVID-19, and is linked to varied clinical outcomes.

Purpose of the Study:

To investigate the association between OP-like patterns on initial chest CT scans and clinical outcomes in patients with mild Coronavirus disease 2019 (COVID-19).
To evaluate the progression of lung involvement in patients with OP-like patterns.

Main Methods:

A cohort of 210 patients with mild COVID-19 underwent initial chest CT scans.
Patients were categorized into two groups: those with (n=103) and without (n=107) typical OP-like patterns.
Clinical outcomes, extent of lung involvement, and serial imaging changes were analyzed.

Main Results:

Patients with OP-like patterns had a significantly longer duration from symptom onset to presentation (7.07 vs. 6.13 days).
The COVID-19-related mortality rate was substantially higher in the OP group (17.5% vs. 3.7%).
Lower lobes were more affected in the OP group, and over 61% showed progression of infiltrations on follow-up CT.

Conclusions:

The presence of an OP-like pattern on initial CT scans in mild COVID-19 patients is associated with a poor prognosis.
Physicians should carefully monitor patients with OP-like patterns and consider interval CT scans to assess disease progression.