Premenstrual Mood Symptoms in the Perimenopause
Bethany Sander1, Jennifer L Gordon2
1Department of Psychology, University of Regina, 3737 Wascana Parkway, Regina, SK, Canada.
Current Psychiatry Reports
|October 6, 2021
Summary
Reproductive aging can worsen menstrually related mood disorders (MRMDs) like premenstrual dysphoric disorder. Treatment may need adjustments during the menopause transition due to hormonal shifts impacting mood sensitivity.
Area of Science:
- Reproductive endocrinology
- Neuroscience
- Psychiatry
Background:
- Menstrually related mood disorders (MRMDs), including premenstrual dysphoric disorder (PMDD), affect many women.
- Reproductive aging, particularly the menopause transition, involves significant hormonal fluctuations.
Purpose of the Study:
- To review the impact of reproductive aging on the course of MRMDs.
- To explore potential adjustments in MRMD treatment during midlife and the menopause transition.
Main Methods:
- Literature review focusing on reproductive aging and mood disorders.
- Analysis of hormonal changes during the menopause transition and their effect on mood.
Main Results:
- Hormonal changes during early perimenopause may exacerbate existing MRMDs.
- Some women exhibit increased mood sensitivity to both rising and falling ovarian hormones during the menopause transition.
Conclusions:
- Healthcare providers should monitor women with a history of MRMDs for symptom worsening during perimenopause.
- Treatment strategies for MRMDs may require modification as women approach and enter midlife.
Keywords:
EstrogenMenopause transitionMenstrually related mood disorders (MRMDs)Premenstrual dysphoric disorder (PMDD)ProgesteroneMore Related Videos
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