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Updated: Oct 17, 2025

Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction
Published on: December 3, 2017
Similar infection rates in a new wound closure method following knee arthroplasty
Shuyang Liu1, Samantha N Andrews2,3, Landon H Morikawa3
1John A Burns School of Medicine, 651 Ilalo Street, Honolulu, HI, 96813, USA.
Abstract:
Surgical site infections, defined as acute wound infections requiring surgical intervention within 90 days post-surgery, were retrospectively compared between a novel, zipper-like closure method (ZM) and staples in 682 patients (904 knees) and 772 patients (971 knees), respectively. The incidence of deep infections was 0.6% for staples and 0.2% for ZM (p = 0.169) and superficial infections was 0.1% for staples and 0.0% for ZM (p = 0.518). With no difference in wound complications, the ZM may be preferred since the two-week post-operative clinic visit required for wound check and staple removal was eliminated, thereby, decreasing clinic volume.
Insights
A novel zipper-like closure method (ZM) showed comparable surgical site infection rates to staples in knee surgery. ZM eliminates the need for a post-operative clinic visit, potentially reducing healthcare system burden.
Area of Science:
- Orthopedic Surgery
- Wound Management
- Infectious Disease
Background:
- Surgical site infections (SSIs) are a significant complication following orthopedic procedures.
- Traditional wound closure methods like staples require follow-up visits for removal and assessment.
- Minimally invasive closure techniques are being explored to improve patient outcomes and reduce healthcare costs.
Purpose of the Study:
- To compare the incidence of surgical site infections between a novel zipper-like closure method (ZM) and traditional staples.
- To evaluate the overall wound complication rates associated with each closure method.
- To assess the potential benefits of ZM in reducing post-operative clinic visits.
Main Methods:
- Retrospective comparative study of 682 patients (904 knees) using ZM and 772 patients (971 knees) using staples.
- Data collected on deep and superficial surgical site infections within 90 days post-surgery.
- Analysis of wound complications and post-operative follow-up requirements.
Main Results:
- The incidence of deep SSIs was 0.2% for ZM versus 0.6% for staples (p=0.169).
- The incidence of superficial SSIs was 0.0% for ZM versus 0.1% for staples (p=0.518).
- No significant difference in overall wound complication rates was observed between the two methods.
Conclusions:
- The zipper-like closure method (ZM) demonstrates non-inferiority to staples in preventing surgical site infections after knee surgery.
- ZM eliminates the need for a two-week post-operative clinic visit for staple removal and wound checks.
- Adoption of ZM could lead to decreased clinic volume and associated healthcare resource utilization.
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