Related Experiment Video
Updated: Oct 17, 2025
06:38
A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies
Published on: April 12, 2017
13.8K
Metastatic Renal Cell Carcinoma Presenting as Gastrointestinal Bleeding
Christopher Hakim1, Avery Mendelson1, Jalpa Patel2
1Department of Internal Medicine, Ascension Providence Hospital - Michigan State University College of Human Medicine, Southfield, Michigan, USA.
Case Reports in Gastroenterology
|October 7, 2021
Summary
Gastric metastasis from renal cell carcinoma (RCC) is rare. This case highlights a patient with advanced RCC successfully treated for a rare gastric tumor caused by metastasis.
Area of Science:
- Oncology
- Gastroenterology
- Pathology
Background:
- Renal cell carcinoma (RCC) is the most common kidney tumor, typically metastasizing to the lungs, bone, and lymph nodes.
- Gastric metastasis from RCC is an exceptionally uncommon presentation.
Observation:
- An 86-year-old woman with known metastatic RCC presented with acute blood loss anemia.
- Esophagogastroduodenoscopy revealed a large, infiltrative, ulcerated polyp in the gastric body.
Findings:
- Histological examination confirmed the gastric polyp was clear-cell carcinoma, consistent with metastatic RCC.
- The patient underwent successful palliative radiation therapy to the gastric lesion.
Implications:
- This case underscores the importance of considering rare metastatic sites in patients with advanced RCC.
- Accurate diagnosis and tailored palliative treatment are crucial for managing rare metastatic presentations of RCC.
More Related Videos
Related Concept Videos
01:28Esophageal Varices-II: Clinical Features and Management
177
Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
177
02:30Metastasis
5.8K
Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
5.8K