Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Drugs for Treatment of Ulcerative Colitis in IBD01:29

Drugs for Treatment of Ulcerative Colitis in IBD

269
Ulcerative colitis is a chronic inflammatory condition primarily affecting the colon and rectum. The primary drugs used in the treatment of ulcerative colitis are aminosalicylates. They exhibit anti-inflammatory and immunosuppressive properties. They modulate inflammatory mediators and inhibit the activity of nuclear factor κB (NF-κB). Aminosalicylates also reduce inflammation by inhibiting prostaglandin and leukotriene production and decreasing neutrophil chemotaxis and superoxide...
269
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

418
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
418
Drugs for Treatment of Constipation-Predominant IBS01:21

Drugs for Treatment of Constipation-Predominant IBS

392
Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
392
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

258
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
258
Drugs Affecting GI Tract Motility: Other Laxatives01:20

Drugs Affecting GI Tract Motility: Other Laxatives

575
Laxatives are primarily used to alleviate constipation, a common gastrointestinal disorder characterized by infrequent bowel movements and difficulty passing stools. They work by various mechanisms to increase the volume or frequency of bowel movements. The primary modes of action of laxatives include increasing stool bulk, softening the stool, stimulating intestinal motility, and osmotically drawing water into the intestines.
Osmotic or saline laxatives, like magnesium hydroxide or milk of...
575
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

457
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
457

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Low-dose Blue Light Extends the Antibacterial Spectrum of Bacitracin Against Escherichia coli.

Journal of global antimicrobial resistance·2026
Same author

Pyogenic liver abscess and pylephlebitis secondary to <i>Klebsiella pneumoniae</i>.

IDCases·2026
Same author

Anthelmintic Resistance in Canine Parasitology: A Critical Review of an Emerging Global Challenge.

Animal health research reviews·2026
Same author

Unmasking the Parasite: When Giardiasis Looks Like Gastroenteritis.

Cureus·2026
Same author

From esophagus to colon: A narrative review of eosinophilic gastrointestinal disorders.

World journal of gastrointestinal pathophysiology·2026
Same author

Development of a qPCR assay for Fasciola spp. identification and a deep amplicon sequencing method for differentiation of fluke species in UK livestock.

PLoS neglected tropical diseases·2026
Same journal

Eosinophilic Gastritis with Localized Eosinophilic Infiltration Presenting as a Solitary Deep-Penetrating Gastric Ulcer Refractory to Potassium-Competitive Acid Blocker.

Case reports in gastroenterology·2026
Same journal

Retrievable Silicone-Covered Esophageal Stent-Assisted Endoscopic Extraction of a High-Risk Clasp-Retained Denture Impacted at the Aortic Arch Level of the Esophagus: A Case Report.

Case reports in gastroenterology·2026
Same journal

Sequential Pancreatic Ascites and Hemosuccus Pancreaticus from an Identical Rupture Site in Branch-Duct Intraductal Papillary Mucinous Neoplasm: A Case Report.

Case reports in gastroenterology·2026
Same journal

Successful Treatment of Refractory Pruritus in Primary Sclerosing Cholangitis with Upadacitinib: A Case Report.

Case reports in gastroenterology·2026
Same journal

Spontaneous Pneumomediastinum Associated with Semaglutide Therapy: A Case Report.

Case reports in gastroenterology·2026
Same journal

De novo Crohn's Disease Treated with Ustekinumab in a Pediatric Liver Transplant Recipient with Tyrosinemia: A Case Report.

Case reports in gastroenterology·2026
See all related articles

Related Experiment Video

Updated: Oct 17, 2025

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection
07:06

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection

Published on: December 8, 2014

27.3K

Colitis Induced by Colon-Cleansing Agent.

Shehriyar Mehershahi1, Haider Ghazanfar2, Shoaib Ashraf2

  • 1Department of Gastroenterology, Bronxcare Health System, Bronx, New York, USA.

Case Reports in Gastroenterology
|October 7, 2021
PubMed
Summary
This summary is machine-generated.

Colon cleansing agents can cause complications in patients with Irritable Bowel Syndrome (IBS). This case highlights the risks of using these products without medical advice, emphasizing the need for caution in managing constipation.

Keywords:
ColitisColon-cleansing agentConstipationIrritable bowel syndrome

More Related Videos

Analyzing Beneficial Effects of Nutritional Supplements on Intestinal Epithelial Barrier Functions During Experimental Colitis
08:58

Analyzing Beneficial Effects of Nutritional Supplements on Intestinal Epithelial Barrier Functions During Experimental Colitis

Published on: January 5, 2017

12.4K
Investigating the Alleviating Effects of Bacillus cereus Administration on Colitis through Gut Microbiota Modulation
08:34

Investigating the Alleviating Effects of Bacillus cereus Administration on Colitis through Gut Microbiota Modulation

Published on: July 27, 2022

959

Related Experiment Videos

Last Updated: Oct 17, 2025

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection
07:06

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection

Published on: December 8, 2014

27.3K
Analyzing Beneficial Effects of Nutritional Supplements on Intestinal Epithelial Barrier Functions During Experimental Colitis
08:58

Analyzing Beneficial Effects of Nutritional Supplements on Intestinal Epithelial Barrier Functions During Experimental Colitis

Published on: January 5, 2017

12.4K
Investigating the Alleviating Effects of Bacillus cereus Administration on Colitis through Gut Microbiota Modulation
08:34

Investigating the Alleviating Effects of Bacillus cereus Administration on Colitis through Gut Microbiota Modulation

Published on: July 27, 2022

959

Area of Science:

  • Gastroenterology
  • Internal Medicine

Background:

  • Constipation is a prevalent functional gastrointestinal disorder affecting 20% of the population.
  • Irritable Bowel Syndrome (IBS) is characterized by chronic abdominal pain and altered bowel habits.

Observation:

  • A 35-year-old male with a history of IBS presented with abdominal pain and bloody diarrhea after using a colon-cleansing agent for constipation.
  • Imaging revealed diffuse mural thickening and nodularity in the colon.
  • Colonoscopy showed moderate to mild inflammation in the colon and ileocecal valve.

Findings:

  • The patient's symptoms improved with symptomatic management.
  • The use of colon-cleansing agents in IBS patients can lead to significant gastrointestinal inflammation and complications.

Implications:

  • Healthcare providers should counsel IBS patients against using colon-cleansing agents without professional guidance.
  • This case underscores the potential adverse effects of over-the-counter gastrointestinal treatments in patients with functional bowel disorders.