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Related Concept Videos

Antiasthma Drugs: Inhaled Corticosteroids and Glucocorticoids01:25

Antiasthma Drugs: Inhaled Corticosteroids and Glucocorticoids

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Inhaled corticosteroids (ICS) are anti-inflammatory drugs used primarily in treating persistent asthma and providing long-term maintenance. They target the bronchial mucosa, the lining of the airways, to control inflammation, a critical factor in asthma progression and exacerbation.
ICS work through a multifaceted mechanism of action. They suppress the inflammatory response caused by the proliferation of TH cells. They also reduce the transcription of the IL-2 gene, which is involved in the...
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COPD: Management Using Bronchodilators and Corticosteroids01:26

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Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
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Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

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Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
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Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics01:23

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Respiratory symptoms, such as congestion and cough, commonly accompany respiratory tract conditions. Various medications, such as antitussives, expectorants, and mucolytics, play crucial roles in providing relief.
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The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
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Antiasthma Drugs: β2-Adrenoceptor Agonists01:25

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Bronchodilators are critical in managing asthma, a chronic respiratory condition characterized by airway constriction due to inflammation and hyper-reactivity. Specifically, bronchodilators ease this constriction by relaxing the bronchial muscles, facilitating easier breathing.
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Related Experiment Video

Updated: Oct 17, 2025

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Antenatal corticosteroids in COVID-19 perspective.

Alex C Vidaeff1, Kjersti M Aagaard2, Michael A Belfort2

  • 1Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Texas Children's Hospital, Baylor College Medicine, Houston, TX 77030, United States. vidaeff@bcm.edu.

World Journal of Experimental Medicine
|October 7, 2021
PubMed
Summary

Antenatal corticosteroids like dexamethasone may benefit hospitalized COVID-19 patients, but their use for fetal maturation in pregnant women with COVID-19 requires careful patient selection based on disease severity to avoid potential harm.

Keywords:
Antenatal corticosteroidsCOVID-19DexamethasonePregnancyPreterm deliverySARS-CoV-2

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Area of Science:

  • Obstetrics and Gynecology
  • Infectious Diseases
  • Neonatal Medicine

Background:

  • The COVID-19 pandemic necessitates adjustments in obstetrical care.
  • Dexamethasone has shown efficacy in treating hospitalized COVID-19 patients.

Purpose of the Study:

  • To discuss the use of antenatal corticosteroids for fetal maturation in pregnant women with COVID-19.
  • To evaluate the risks and benefits of dexamethasone based on disease severity.

Main Methods:

  • Review of recent high-quality evidence on dexamethasone treatment for COVID-19.
  • Analysis of randomized disease outcome data correlating treatment with disease stage.

Main Results:

  • Dexamethasone benefits hospitalized COVID-19 patients with severe disease.
  • Patients with mild COVID-19 may not benefit and could experience harm from dexamethasone.
  • Indiscriminate use of corticosteroids for fetal maturation is not advised.

Conclusions:

  • Antenatal corticosteroid administration for fetal maturation in COVID-19 positive pregnant women should be guided by disease severity.
  • Risk stratification and careful candidate selection are crucial for optimizing obstetrical care during the pandemic.