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Related Concept Videos

The Cochlea01:13

The Cochlea

47.4K
The cochlea is a coiled structure in the inner ear that contains hair cells—the sensory receptors of the auditory system. Sound waves are transmitted to the cochlea by small bones attached to the eardrum called the ossicles, which vibrate the oval window that leads to the inner ear. This causes fluid in the chambers of the cochlea to move, vibrating the basilar membrane.
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Hair Cells01:22

Hair Cells

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Hair cells are the sensory receptors of the auditory system—they transduce mechanical sound waves into electrical energy that the nervous system can understand. Hair cells are located in the organ of Corti within the cochlea of the inner ear, between the basilar and tectorial membranes. The actual sensory receptors are called inner hair cells. The outer hair cells serve other functions, such as sound amplification in the cochlea, and are not discussed in detail here.
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Updated: Oct 17, 2025

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Low-Frequency Sensorineural Hearing Loss Associated With Iron-Deficiency Anemia.

Masakatsu Taki1, Tatsuhisa Hasegawa2, Yuzuru Ninoyu1

  • 1Department of Otolaryngology-Head and Neck Surgery, Kyoto Prefectural University of Medicine, Kyoto, Kyoto, Japan.

The Journal of International Advanced Otology
|October 7, 2021
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Summary

Acute low-frequency hearing loss (ALHL) without vertigo may be linked to iron-deficiency anemia (IDA). Treating IDA with iron sucrose effectively resolved hearing loss in one patient, suggesting a novel therapeutic approach.

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Area of Science:

  • Otolaryngology
  • Hematology
  • Internal Medicine

Background:

  • Acute low-frequency hearing loss (ALHL) without vertigo is often associated with cochlear hydrops or early Meniere's disease.
  • The underlying mechanisms for some ALHL cases remain unclear.

Observation:

  • A 49-year-old female presented with recurrent ALHL, diagnosed as cochlear hydrops.
  • Initial treatments including isosorbide, betamethasone, and intravenous hydrocortisone were ineffective.

Findings:

  • The patient had concurrent iron-deficiency anemia (IDA).
  • Intravenous iron sucrose administration for IDA led to gradual hearing loss resolution within two months.
  • Hearing improvement correlated with increased serum hemoglobin levels.

Implications:

  • This case suggests a potential association between ALHL and IDA.
  • Iron deficiency may be a contributing factor to ALHL in some patients.
  • Intravenous iron therapy could be a viable treatment for ALHL in cases associated with IDA.