Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Structural Joints: Fibrous Joints01:03

Structural Joints: Fibrous Joints

2.9K
Fibrous joints are a type of joint where the bones are connected by fibrous connective tissue. These joints provide stability and minimal to no movement between the articulating bones. There are three types of fibrous joints.
Suture
All the bones of the skull, except for the mandible, are joined to each other by a fibrous joint called a suture. The fibrous connective tissue found at a suture strongly unites the adjacent skull bones and thus helps to protect the brain and form the face. In...
2.9K
Compact Bone01:27

Compact Bone

14.2K
Most bones contain compact and spongy osseous tissue, but their distribution and concentration vary based on the bone's overall function.
Compact bone, also called cortical bone, is the denser, stronger of the two types of bone tissue. It is found under the periosteum and in the diaphyses of long bones, where it provides support and protection. The microscopic structural unit of compact bone is called an osteon, or haversian system. Each osteon is composed of concentric rings of calcified...
14.2K
Spongy Bone01:09

Spongy Bone

6.1K
All bones comprise an outer layer of compact bone, and an interior made up of spongy bone tissue, also called cancellous or trabecular bone. In long bones, spongy bone tissue is mainly found in the interior of the epiphyses (broad ends of the bone).
Spongy bone is more porous, and less dense compared to compact bone. It is composed of concentric lamellae that are arranged irregularly to form the trabecular network. In some bones, the spaces between trabeculae contain red marrow, where...
6.1K
Bone Formation by Intramembranous Ossification01:29

Bone Formation by Intramembranous Ossification

8.5K
Intramembranous ossification is one of the two processes involved in the development of bones within an embryo. The flat bones of the face, most of the cranial bones, and the clavicles are formed via this process. During intramembranous ossification, the bones develop directly from sheets of undifferentiated mesenchymal connective tissue.
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into ...
8.5K
Gross Anatomy of Bone01:17

Gross Anatomy of Bone

7.4K
The two main features of a long bone are the diaphysis and the epiphysis.
The diaphysis is the tubular shaft that runs between the proximal and distal ends of the bone. The walls of the diaphysis are composed of dense and hard compact bone made of numerous osteons — the functional unit of the compact bone. The hollow region in the diaphysis is called the medullary cavity, which harbors the bone marrow. In infants and children, this marrow cavity is filled with red marrow, whereas in...
7.4K
Osteoclasts in Bone Remodeling01:31

Osteoclasts in Bone Remodeling

3.4K
Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during...
3.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Errate: Limb-Salvage Outcomes of Arterial Repair Beyond Time Limit at Different Lower-Extremity Injury Sites.

Medical science monitor : international medical journal of experimental and clinical research·2026
Same author

Aloe vera polysaccharides facilitate diabetic wound healing by promoting macrophage M<sub>2</sub> polarization through inhibition of NLRP3 inflammasome activation.

Phytomedicine : international journal of phytotherapy and phytopharmacology·2026
Same author

Mechanical Processing of SVF-Enriched Microfat for Reconstruction of Traumatic Soft Tissue Defects.

Journal of visualized experiments : JoVE·2026
Same author

Enhanced external counterpulsation-assisted cannulated screw fixation promoted femoral neck fracture healing: a pilot randomized controlled trial.

BMC musculoskeletal disorders·2025
Same author

Synergistic photothermal-sonodynamic therapy for antibacterial and immune reprogramming in chronic osteomyelitis.

Journal of controlled release : official journal of the Controlled Release Society·2025
Same author

Drug-Free "Triboelectric Immunotherapy" Activating Immunity for Osteomyelitis Treatment and Recurrence Prevention.

Advanced materials (Deerfield Beach, Fla.)·2024

Related Experiment Video

Updated: Oct 17, 2025

Modeling Primary Bone Tumors and Bone Metastasis with Solid Tumor Graft Implantation into Bone
06:53

Modeling Primary Bone Tumors and Bone Metastasis with Solid Tumor Graft Implantation into Bone

Published on: September 9, 2020

3.0K

Fibro-Osseous Pseudotumor.

Di Liu, Baiwen Qi, Zhen Huang

    Orthopedics
    |October 7, 2021
    PubMed
    Summary
    This summary is machine-generated.

    Fibro-osseous pseudotumor is a rare, benign ossifying lesion often misdiagnosed as malignant. This case highlights accurate diagnosis and treatment to avoid unnecessary radical surgery for this hand and toe tumor.

    More Related Videos

    Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors
    08:57

    Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors

    Published on: May 17, 2024

    2.2K
    Laminectomy for the Removal of Thoracic Ossification of the Ligamentum Flavum TOLF Using Ultrasonic and Conventional Osteotomes
    07:12

    Laminectomy for the Removal of Thoracic Ossification of the Ligamentum Flavum TOLF Using Ultrasonic and Conventional Osteotomes

    Published on: April 21, 2023

    2.9K

    Related Experiment Videos

    Last Updated: Oct 17, 2025

    Modeling Primary Bone Tumors and Bone Metastasis with Solid Tumor Graft Implantation into Bone
    06:53

    Modeling Primary Bone Tumors and Bone Metastasis with Solid Tumor Graft Implantation into Bone

    Published on: September 9, 2020

    3.0K
    Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors
    08:57

    Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors

    Published on: May 17, 2024

    2.2K
    Laminectomy for the Removal of Thoracic Ossification of the Ligamentum Flavum TOLF Using Ultrasonic and Conventional Osteotomes
    07:12

    Laminectomy for the Removal of Thoracic Ossification of the Ligamentum Flavum TOLF Using Ultrasonic and Conventional Osteotomes

    Published on: April 21, 2023

    2.9K

    Area of Science:

    • Orthopedic Surgery
    • Pathology
    • Radiology

    Background:

    • Fibro-osseous pseudotumor is an exceptionally rare subcutaneous benign ossifying lesion.
    • It most commonly affects the hands and toes, characterized by bone formation.
    • Its invasive nature often leads to misdiagnosis as malignancy, resulting in overtreatment.

    Observation:

    • A case report details a 32-year-old male patient with fibro-osseous pseudotumor on the left index finger.
    • Comprehensive diagnostic, treatment, and follow-up data were meticulously documented.
    • The study includes a review of previously published cases to enhance understanding.

    Findings:

    • The benign nature of fibro-osseous pseudotumor can be obscured by its local invasiveness.
    • Accurate diagnostic criteria are crucial to differentiate it from malignant neoplasms.
    • This case underscores the importance of precise diagnosis in guiding appropriate management.

    Implications:

    • Improved diagnostic accuracy for fibro-osseous pseudotumor can prevent radical and excessive surgical interventions.
    • This research contributes to refining diagnostic criteria for this rare ossifying lesion.
    • Enhanced understanding may lead to more conservative and effective treatment strategies.