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A Web Tool for Generating High Quality Machine-readable Biological Pathways
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A field guide to cultivating computational biology
Gregory P Way1,2, Casey S Greene2, Piero Carninci3,4
1Imaging Platform, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America.
Plos Biology
|October 7, 2021
Summary
Computational biology has advanced significantly but faces career development challenges. Solutions are proposed to enhance recognition and promote multidisciplinary team science for future discoveries.
Area of Science:
- Computational biology
- Bioinformatics
- Systems biology
Background:
- Computational biology has matured over 30 years, contributing to scientific knowledge and human health.
- Despite its impact, individual practitioners often face career development hurdles.
- There's a need to address the disparity between scientific progress and career progression in the field.
Purpose of the Study:
- To propose actionable solutions for advancing computational biology careers.
- To encourage broader adoption and integration of computational biology across institutions.
- To foster a more supportive environment for computational biologists.
Main Methods:
- The study outlines 10 steps for scientists, institutions, publishers, funding agencies, and educators.
- It advocates for a shift from traditional single-discipline research to multidisciplinary, data-driven team science.
- The approach emphasizes improving recognition and aligning career paths with scientific advancement.
Main Results:
- The proposed solutions aim to fully embrace computational biology.
- Implementing these steps is expected to improve career development for computational biologists.
- A move towards team science is highlighted as crucial for future breakthroughs.
Conclusions:
- Enhancing recognition and aligning career success with scientific progress are vital.
- Adopting multidisciplinary, data-driven team science is essential for the next generation of discoveries.
- Collective action from various stakeholders is needed to fully realize the potential of computational biology.
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