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Updated: Oct 17, 2025

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2
Published on: November 5, 2021
Origins of SARS-CoV-1 and SARS-CoV-2 are often poorly explored in leading publications
1Carnegie Museum of Natural History, Powdermill Nature Reserve, 1795 Route 381, Pittsburgh, PA, 15677, USA.
Abstract:
In the rush to understand the coronaviruses that threaten human health, authors of many prominent papers have not performed phylogenetic analyses to the standard of the field today. Errors include faulty placement of the root of the phylogeny, outdated methods of reconstruction, poor taxon sampling, inappropriate emphasis on selected functional elements, and inadequate consideration of ambiguity. As a result, certain conclusions regarding the origin of human infections are not supported soundly or are wrong.
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