Comparison of semiology in patients with psychogenic nonepileptic seizures or with epilepsy in Puerto Rico

The aims of this study were to develop a descriptive profile of patients with psychogenic nonepileptic seizures (PNES) in Puerto Rico who have been evaluated using an epilepsy monitoring unit. The other aim was to establish comparisons between the clinical manifestation of PNES and events of generalized epilepsy (GE).

A retrospective study was conducted to evaluate the information of patients who passed through the Epilepsy Unit in Caguas, Puerto Rico. In the first phase, sociodemographic information of 100 patients with PNES was collected. In the second phase, a sample of 51 cases was obtained; 37 cases with a final diagnosis of PNES and 14 cases with the diagnosis of GE. Observations were made with the objective of viewing and comparing the semiology and clinical manifestation presented through video encephalograms (vEEG) in both subsamples.

Patients with PNES and epilepsy demonstrated different semiological patterns. Psychogenic nonepileptic seizures is predominant in females (95%). Most patients with epilepsy presented a relatively short seizure (<2 min) compared with patients with PNES (79% vs. 46%). Patients with epilepsy showed a slow return to their baseline manifestation (100% vs. 11%). Specifically, having their eyes closed, extreme asynchronous limb movements, and rigidity were statistically significant.

These findings provide evidence that the semiology of patients with PNES is different from those displaying an epileptic seizure. This study supports the idea that the semiology of Latino patients with PNES is similar to the characteristics reported in other countries.