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Updated: Oct 17, 2025

Frailty Assessment in an Aging Mouse Model
Published on: September 23, 2025
[Frailty, a perspective along the time.]
1Jefe de Servicio de Geriatría. Hospital Universitario de Getafe. Madrid. España.
Frailty, a condition gaining prominence, is increasingly recognized as a key factor impacting quality of life. This review explores its history, detection, management, and future challenges in healthcare.
Area of Science:
- Gerontology and Public Health
- Epidemiology of Aging Populations
Background:
- 20th-century demographic shifts altered population structures and epidemiological profiles.
- Healthcare focus evolved from delaying death to preventing disability and improving quality of life.
- Frailty, a relatively new nosological entity, has gained significant clinical and research attention.
Purpose of the Study:
- To provide a historical review of the conceptualization and definition of frailty.
- To examine the challenges in frailty detection and diagnosis.
- To outline strategies for frailty management, prevention, and healthcare system adaptation.
Main Methods:
- Historical analysis of frailty's conceptual evolution.
- Review of diagnostic challenges and management approaches.
- Examination of national and supranational organizational efforts.
Main Results:
- Frailty's conceptual frameworks have been defined and delimited over time.
- Detection and diagnosis of frailty present significant challenges.
- Management strategies encompass prevention, individual treatment, and health system adjustments.
Conclusions:
- Frailty is a critical factor influencing quality of life and healthcare demands.
- Addressing frailty requires integrated health and social system adaptations.
- Ongoing research and care efforts are essential to meet the challenges posed by frailty.
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