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Updated: Oct 17, 2025

An Orthotopic Bladder Cancer Model for Gene Delivery Studies
Published on: December 1, 2013
Carbon ion radiotherapy for bladder cancer: A case report
Yan-Shan Zhang1, Xiao-Jun Li2, Yi-He Zhang2
1Heavy Ion Center, Wuwei Cancer Hospital, Wuwei 733000, Gansu Province, China. 13830510999@163.com.
Background:
Radical cystectomy is considered the first choice for the treatment of muscle-invasive bladder cancer. However, for some patients who have lost the indications for surgery, external beam radiotherapy is a non-invasive and effective treatment.
Case Summary:
A 76-year-old patient with bladder cancer who had serious comorbidities and could not tolerate surgery or chemotherapy came to the Wuwei Heavy Ion Center. He received carbon ion radiotherapy (CIRT) with a whole-bladder dose of 44 GyE and tumor boost of 20 GyE. When he finished CIRT, his bladder cancer-related hematuria completely disappeared, and computed tomography examination showed that the tumor had obviously decreased in size. At the 3-mo follow-up, the tumor disappeared, and there were no acute or late adverse events. CIRT was well tolerated in this patient.
Conclusion:
CIRT may allow for avoiding resection and was well tolerated with curative outcomes.

