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Prepubertal acne: A retrospective study.

Cécile Frénard1, Siham Mansouri1, Stéphane Corvec2

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Summary
This summary is machine-generated.

Prepubertal acne affects 3.5% of acne patients, being more common in females. Severe acne, milk consumption, and other medications predict poor treatment response in children.

Keywords:
Prepubertal acneacneepidemiologyrisk factors

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Area of Science:

  • Dermatology and Pediatric Skin Health
  • Epidemiology of Skin Conditions
  • Microbiology of Cutibacterium acnes

Background:

  • Limited epidemiological data exists for prepubertal acne vulgaris.
  • Understanding prepubertal acne is crucial due to its potential for long-term impact.
  • Acne vulgaris is a prevalent skin disorder affecting various age groups.

Purpose of the Study:

  • To determine the prevalence and severity of acne in prepubertal children (7-12 years).
  • To identify factors associated with acne severity in this age group.
  • To identify predictors of poor treatment response or resistance in prepubertal acne patients.

Main Methods:

  • Retrospective analysis of 683 acne patients from October 2014 to May 2018.
  • Inclusion criteria focused on patients aged 7-12 years diagnosed with prepubertal acne.
  • Utilized the Groupe Expert Acné and Global Evaluation Acne Group scales for severity assessment.

Main Results:

  • Prepubertal acne was identified in 3.5% of the acne patient cohort, with a higher prevalence in females (75%).
  • Severe acne (grade 4) was the most frequent presentation (33%), with mild and moderate forms at 25% each.
  • Factors linked to poor treatment response included initially severe acne (grade 4), regular milk consumption, and concurrent medication use.

Conclusions:

  • Prepubertal acne presents unique epidemiological and clinical features.
  • Severe initial grading, milk intake, and polypharmacy are significant risk factors for treatment failure in pediatric acne.
  • Prompt and appropriate management is essential to mitigate disease severity and prevent long-term consequences.