aVR ST-segment changes and prognosis of ST-segment elevation myocardial infarction.
Sogol Sedighi1, Mustafa Fattahi1, Pooyan Dehghani1
1Cardiovascular Research Center Shiraz University of Medical Sciences Shiraz Iran.
Health Science Reports
|October 8, 2021
Summary
ST-segment changes in the aVR lead can predict outcomes in ST-segment elevation myocardial infarction (STEMI). aVR ST elevation predicts major adverse cardiovascular events in anterior STEMI, while aVR ST depression predicts events in inferior STEMI.
Area of Science:
- Cardiology
- Electrocardiography
- Myocardial Infarction Research
Background:
- The prognostic value of aVR lead ST-segment changes in acute myocardial infarction (AMI) is not fully established.
- Understanding these changes is crucial for predicting patient outcomes following AMI.
Purpose of the Study:
- To evaluate the predictive value of ST-segment variations in the aVR lead for outcomes in patients experiencing their first ST-segment elevation myocardial infarction (STEMI).
- To assess the association between aVR lead changes and major adverse cardiovascular events (MACE) within 30 days post-STEMI.
Main Methods:
- Prospective cohort study of first-episode STEMI patients undergoing percutaneous coronary intervention.
- Electrocardiogram (ECG) data collected upon hospital admission.
- Follow-up for 30 days to monitor cardiovascular complications.
Main Results:
- In anterior STEMI, admission aVR ST elevation ≥1 mm independently predicted 30-day MACE (P-trend=.002).
- In inferior STEMI (± RV), admission aVR ST depression ≥1 mm independently predicted 30-day MACE (P-trend=.01).
Conclusions:
- Admission aVR ST elevation ≥1 mm is a strong predictor of MACE in anterior STEMI patients within 30 days.
- Admission aVR ST depression ≥1 mm is a strong predictor of MACE in inferior STEMI patients within 30 days.
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