aVR ST-segment changes and prognosis of ST-segment elevation myocardial infarction
Sogol Sedighi1, Mustafa Fattahi1, Pooyan Dehghani1
1Cardiovascular Research Center Shiraz University of Medical Sciences Shiraz Iran.
Insights
ST-segment changes in the aVR lead can predict outcomes in ST-segment elevation myocardial infarction (STEMI). aVR ST elevation predicts major adverse cardiovascular events in anterior STEMI, while aVR ST depression predicts events in inferior STEMI.
Area of Science:
- Cardiology
- Electrocardiography
- Myocardial Infarction Research
Background:
- The prognostic value of aVR lead ST-segment changes in acute myocardial infarction (AMI) is not fully established.
- Understanding these changes is crucial for predicting patient outcomes following AMI.
Purpose of the Study:
- To evaluate the predictive value of ST-segment variations in the aVR lead for outcomes in patients experiencing their first ST-segment elevation myocardial infarction (STEMI).
- To assess the association between aVR lead changes and major adverse cardiovascular events (MACE) within 30 days post-STEMI.
Main Methods:
- Prospective cohort study of first-episode STEMI patients undergoing percutaneous coronary intervention.
- Electrocardiogram (ECG) data collected upon hospital admission.
- Follow-up for 30 days to monitor cardiovascular complications.
Main Results:
- In anterior STEMI, admission aVR ST elevation ≥1 mm independently predicted 30-day MACE (P-trend=.002).
- In inferior STEMI (± RV), admission aVR ST depression ≥1 mm independently predicted 30-day MACE (P-trend=.01).
Conclusions:
- Admission aVR ST elevation ≥1 mm is a strong predictor of MACE in anterior STEMI patients within 30 days.
- Admission aVR ST depression ≥1 mm is a strong predictor of MACE in inferior STEMI patients within 30 days.
Background:
Clinical importance of aVR lead-related changes in predicting the prognosis of acute myocardial infarction remains uncertain. The present study aimed to assess the value of ST-segment changes in aVR lead and the outcome and sequels of the first episode of acute ST-segment elevation myocardial infarction.
Methods:
This prospective cohort study was conducted on patients suffering first episode of ST-segment elevation myocardial infarction and underwent percutaneous coronary intervention. Information was collected through hospital-recorded files reading. The electrocardiogram (ECG) was taken from the patients upon entering the hospital and followed-up for 30 days to assess cardiovascular complications.
Results:
In patients with anterior STEMI, with the use of multivariate analysis, admission aVR ST elevation ≥1 mm was found to be a strong and independent predictor of major cardiovascular adverse events (MACE) within 30 days of discharging (P value for trend .002). In patients with inferior (± RV) ST-segment elevation myocardial infarction (STEMI), with the use of multivariate analysis, admission aVR ST depression ≥1 mm was found to be a strong and independent predictor of MACE within 30 days of discharging (P value for trend .01).
Conclusion:
In patients with anterior STEMI, admission aVR STE ≥1 mm was found to be a strong and independent predictor of MACE within 30 days of discharging. On the other hand, in patients with inferior STEMI, aVR ST depression ≥1 mm was found to be a strong and independent predictor of MACE within 30 days of discharging.
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