Treatment of essential hypertension with pindolol

Pindolol was given for 12-15 consecutive weeks to 35 patients for the treatment of essential hypertension. Significant blood pressure reductions were achieved in the group of 28 patients who completed the trial, as tested by the Wilcoxon pair test. There was no difference in antihypertensive effect between a three times a day and a twice a day administration schedule. The incidence of side-effects was not affected by the change in dosage or schedule.