Related Experiment Video
Updated: Oct 17, 2025

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
Published on: November 4, 2010
[Clinical Analysis of 86 Cases of Children with Plastic Bronchitis]
Ling-Li Shu1, Lin Zhong1, Li Qiu1
1Department of Pediatric Pulmonology and Immunology, West China Second University Hospital, Sichuan University, Chengdu 610041, China.
Insights
Pediatric plastic bronchitis (PB) often presents with severe symptoms and complications. Young children and those with complications require respiratory support, highlighting key risk factors for early identification.
Area of Science:
- Pediatric Pulmonology
- Infectious Diseases
- Critical Care Medicine
Background:
- Plastic bronchitis (PB) is a rare but serious condition in children.
- Identifying risk factors for respiratory support is crucial for timely intervention.
- Understanding clinical features aids in early diagnosis of pediatric PB.
Purpose of the Study:
- To characterize the clinical presentation of pediatric plastic bronchitis.
- To identify independent risk factors associated with the need for respiratory support in children with PB.
- To enhance the clinical recognition of PB in pediatric patients.
Main Methods:
- Retrospective analysis of 86 pediatric patients diagnosed with PB.
- Data collected on clinical manifestations, complications, and treatment (respiratory support).
- Logistic regression used to determine risk factors for respiratory support.
Main Results:
- Most patients (72.1%) were over 3 years old, with 66.3% experiencing complications.
- Severe symptoms like high fever (≥39.5°C), extensive lung consolidation/atelectasis (95.3%), and pleural effusion (73.3%) were common.
- Mycoplasma pneumoniae was the most frequent pathogen (68.6%). Patients younger than 3 years (OR=4.99) and those with complications (OR=7.22) had significantly higher odds of requiring respiratory support.
Conclusions:
- Severe symptoms, systemic complications, significant lung abnormalities, and Mycoplasma pneumoniae infection warrant suspicion for PB.
- Younger age (<3 years) and the presence of complications are independent predictors of respiratory support need in pediatric PB.
- These findings can improve early identification and management of plastic bronchitis in children.
Objective:
To investigate the clinical features of pediatric patients who had plastic bronchitis (PB) and to explore the risk factors for respiratory support in the pediatric patients with PB in order to improve the ability to identify PB in children.
Methods:
The basic information and clinical manifestations of 86 children diagnosed with PB at West China Second University Hospital of Sichuan University from March 2014 to December 2019 were collected and analyzed retrospectively. The patients were divided into the respiratory support (RS) group and non-respiratory support (NRS) group as per their need for respiratory support. Logistic regression was conducted to analyze the risk factors for respiratory support in PB patients.
Results:
A total of 86 children with PB were included in the study, including 62 (72.1%) who were over 3 years old. 57 patients (66.3%) had complications. 56 patients were given respiratory support after admission. All the 86 children had a history of fever and cough, and 76 (88.4%) experienced fever peaks≥39.5°C. Chest imaging showed large lung consolidation or atelectasis in 82 cases (95.3%) and pleural effusion in 63 cases (73.3%). 70 cases (81.4%) were tested positive for pathogens, with the highest infection rate of 68.6% for mycoplasma pneumoniae. There were 30 patients (34.9%) in the NRS group and 56 patients (65.1%) in the RS group. Logistic regression analysis showed that patient being younger than 3 years old ( OR=4.99) and having complications ( OR=7.22) were independent risk factors for respiratory support in children with PB (all P<0.05).
Conclusions:
Clinically, severe clinical symptoms combined with other systemic complications, large lung consolidation or atelectasis, pleural effusion, and positive lab results for mycoplasma pneumoniae should be an alert indicating the possibility of having PB. Young age and complications were independent risk factors for respiratory support in PB patients.
Related Concept Videos
Pulmonary Cycle: Exhalation
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
Medical History
Chronic Obstructive Pulmonary Disease-I: Introduction
Physical Assessment of the Respiratory Tract I: Health History
Subjective Data
Subjective data provides vital information about the patient's health history and symptoms. This data is typically collected through interviews in which patients describe their experiences, symptoms, and concerns.
Health history and...
Chronic Obstructive Pulmonary Disease-II: Pathophysiology
Chronic Inflammation
COPD: Management Using Bronchodilators and Corticosteroids

