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COVID-19 myocarditis cardiac magnetic resonance findings in symptomatic patients

Sedat Altay1

  • 1Department of Radiology, 485550Izmir Katip Celebi University Ataturk Research and Training Hospital, İzmir, Turkey.

Acta Radiologica (Stockholm, Sweden : 1987)
|October 8, 2021
PubMed

Insights

Cardiac magnetic resonance (CMR) detected abnormalities in 46% of COVID-19 patients, indicating myocardial damage. While CMR can identify cardiac involvement, no specific imaging features distinguish COVID-19 myocarditis.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Medical Imaging

Background:

  • Coronavirus disease 2019 (COVID-19) is known to potentially cause myocardial damage.
  • Understanding the cardiac implications of COVID-19 is crucial for patient management.

Purpose of the Study:

  • To assess short-term and medium-term outcomes of cardiac involvement in COVID-19 patients.
  • To identify characteristic imaging features of COVID-19-related cardiac conditions using cardiac magnetic resonance (CMR).

Main Methods:

  • Retrospective analysis of laboratory and CMR findings in 15 COVID-19 patients (May 2020-May 2021).
  • Evaluation of late gadolinium enhancement (LGE) for myocarditis.
  • Quantitative assessment of cardiac function and comparison with a control group.
  • Correlation analysis between high-sensitivity cardiac troponin I (Hs-cTnI), C-reactive protein (CRP), and LGE.

Main Results:

  • CMR abnormalities were detected in 46% of COVID-19 patients.
  • Late gadolinium enhancement (LGE) was observed in 33% of home-treated and 55.5% of hospitalized patients.
  • Elevated Hs-cTnI and CRP levels were noted in hospitalized patients, with a strong correlation between Hs-cTnI and LGE (r=0.63, P<0.001).
  • No significant difference in ventricular function was found between COVID-19 and control groups (P<0.001).

Conclusions:

  • Cardiac magnetic resonance (CMR) is effective in detecting myocardial abnormalities in COVID-19 patients.
  • A significant percentage of COVID-19 patients exhibit CMR-detected cardiac abnormalities.
  • No specific diagnostic imaging feature for COVID-19 myocarditis was identified via CMR.
Abstract

Keywords:
COVID-19cardiac functionscardiac involvementcardiac magnetic resonance imagingmyocarditis

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