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A Comprehensive Review on Thiophene Based Chemosensors
Rikitha S Fernandes1, Nitinkumar S Shetty2, Priyanka Mahesha1
1Department of Chemistry, Manipal Institute of Technology, Manipal Academy of Higher Education, 576104, Manipal, Karnataka, India.
Journal of Fluorescence
|October 8, 2021
Summary
This review explores thiophene-based chemosensors for detecting analytes. These probes offer high selectivity and sensitivity for sensing applications in aqueous and biological systems.
Area of Science:
- Analytical Chemistry
- Organic Chemistry
- Materials Science
Background:
- Fluorometric and colorimetric chemosensors are crucial for analyte detection in various systems.
- Thiophene derivatives exhibit superior photophysical properties, making them promising for chemosensor development.
- There is a growing need for selective, sensitive, and cost-effective sensing technologies.
Purpose of the Study:
- To review the design and detection mechanisms of thiophene-based chemosensors.
- To explore the practical applications and advanced design principles of these probes.
- To provide insights for synthesizing novel thiophene-based chemosensors.
Main Methods:
- Literature review of thiophene-based chemosensors reported between 2008 and 2020.
- Analysis of emission and absorption-based detection strategies.
- Examination of probe design and their structure-property relationships.
Main Results:
- Thiophene scaffolds are effective in developing emission and absorption-based chemosensors.
- Various thiophene derivatives demonstrate high selectivity and sensitivity for different analytes.
- Design guides for advanced thiophene-based probes have been identified.
Conclusions:
- Thiophene-based chemosensors represent a significant advancement in analyte detection.
- The review highlights the versatility and potential of thiophene derivatives in sensor technology.
- Future research can leverage these findings for the development of next-generation chemosensors.
