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Updated: Oct 17, 2025

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Robotic Central Pancreatectomy with Roux-en-Y Pancreaticojejunostomy
Published on: November 20, 2021
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Robotic central pancreatectomy: a systematic review and meta-analysis
Gianluca Rompianesi1, Roberto Montalti1, Mariano C Giglio1
1Division of Hepato-Bilio-Pancreatic, Minimally Invasive and Robotic Surgery, Department of Clinical Medicine and Surgery, Federico II University Hospital, Naples, Italy.
Summary
Robotic central pancreatectomy (RCP) is a safe procedure for pancreatic tumors, showing low mortality. However, high rates of pancreatic fistula and overall complications require careful consideration.
Area of Science:
- Gastroenterology
- Surgical Oncology
- Robotic Surgery
Background:
- Central pancreatectomy is a standard procedure for pancreatic neck/body lesions.
- Robotic technology has enabled minimally invasive central pancreatectomies.
- This review systematically analyzes outcomes of robotic central pancreatectomies (RCP).
Purpose of the Study:
- To appraise the results and outcomes of robotic central pancreatectomies (RCP).
- To conduct a systematic review and meta-analysis of existing literature on RCP.
Main Methods:
- Systematic literature search across MEDLINE, Embase, and Web of Science.
- Inclusion of thirteen series comprising 265 patients undergoing RCP.
- Pooled prevalence rates of postoperative complications and mortality calculated using random-effect modeling.
Main Results:
- RCP predominantly used for benign or low-grade tumors.
- High incidence of clinically relevant post-operative pancreatic fistula (POPF) at 42.3%.
- Overall complications at 57.5%, with severe complications (Clavien-Dindo ≥ III) in 9.4%; low re-operation (0.7%), new-onset diabetes (0.3%), mortality, and conversion rates.
Conclusions:
- Robotic central pancreatectomy (RCP) demonstrates safety with low perioperative mortality.
- Postoperative pancreatic function is generally well-preserved after RCP.
- High rates of overall morbidity and POPF are notable challenges of RCP.

