[Research and Application Progress of Chitosan-based Hemostatic Materials---Review]

Area of Science:

• Biomaterials Science
• Polymer Chemistry
• Medical Technology

Background:

• Effective hemostasis is critical for improving survival rates in wounded individuals.
• Current commercial hemostatic materials (natural, synthetic, mineral, coagulation components) have inherent limitations.
• There is a global effort to develop superior hemostatic agents for emergency care.

Purpose of the Study:

• To review the characteristics of chitosan and its derivatives as natural organic macromolecular polysaccharide hemostasis materials.
• To analyze their molecular structures, biomedical properties, and research progress.
• To compare chitosan-based materials with other hemostatic agents.

Main Methods:

• Literature review of chitosan and its derivatives in hemostasis.
• Analysis of molecular structures and biomedical properties.
• Comparative assessment of current hemostatic material applications.

Main Results:

• Chitosan and its derivatives are effective natural hemostatic agents.
• These materials offer advantages over some existing hemostatic products.
• Existing research highlights their potential in various biomedical applications.

Conclusions:

• Chitosan-based materials represent a significant advancement in natural hemostatic agents.
• Further innovation is needed to optimize chitosan composites.
• Future development should focus on multifunctional chitosan materials for hemostasis, antibiosis, pain relief, and wound healing.