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Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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Open Angle Glaucoma: Treatment01:27

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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
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Angle Closure Glaucoma: Treatment01:28

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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Intraocular Pressure Changes in the Contralateral Eye After Glaucoma Surgery.

Aidin Meshksar1,2, Maryam Hajizadeh3, Farideh Sharifipour1,4

  • 1Ophthalmic Research Center, Research Institute for Ophthalmology and Vision Science, Shahid Beheshti University of Medical Sciences.

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Summary

Glaucoma surgery can cause significant intraocular pressure (IOP) elevation in the fellow eye, particularly after drainage device implantation. Monitoring IOP in the unoperated eye post-surgery is crucial.

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Area of Science:

  • Ophthalmology
  • Glaucoma Research
  • Surgical Outcomes

Background:

  • Glaucoma surgery in one eye may lead to increased intraocular pressure (IOP) in the fellow eye.
  • This contralateral IOP elevation is more pronounced after glaucoma drainage device implantation and in cases of postoperative hypotony.

Purpose of the Study:

  • To investigate the temporal changes and magnitude of intraocular pressure (IOP) fluctuations in the fellow eye after glaucoma surgery.

Main Methods:

  • A study of 131 glaucoma patients undergoing surgery.
  • Recorded IOP changes and medication use in fellow eyes for six months.
  • Defined significant IOP elevation as ≥4 mmHg or a 20% increase from baseline.

Main Results:

  • Fellow eye IOP significantly increased post-surgery, peaking at 1 week (mean increase 3.1±3.2 mmHg) and gradually decreasing over 6 months.
  • Clinically significant IOP elevation occurred in 47-76% of fellow eyes within the first week.
  • Contralateral IOP elevation was linked to tube shunt surgery, prior cataract surgery, low initial postoperative IOP, and acetazolamide use.

Conclusions:

  • Glaucoma surgery is associated with significant IOP elevation in a substantial proportion of fellow eyes.
  • Routine monitoring of IOP in the unoperated eye during postoperative visits is recommended.