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Radiation: Applications01:17

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The average temperature of Earth is the subject of much current discussion. Earth is in radiative contact with both the Sun and dark space; it receives almost all its energy from the radiation of the Sun and reflects some of it into outer space. Dark space is very cold, about 3 K, so Earth radiates energy into it. For instance, heat transfer occurs from soil and grasses, the rate of which can be so rapid that frost can occur on clear summer evenings, even in warm latitudes.
The average...
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Radiation Segmentectomy.

Kristina Prachanronarong1, Edward Kim1

  • 1Department of Interventional Radiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Health System, New York, New York.

Seminars in Interventional Radiology
|October 11, 2021
PubMed
Summary
This summary is machine-generated.

Radiation segmentectomy, a precise yttrium-90 transarterial radioembolization, delivers targeted radiation for liver tumors. It shows effectiveness as a neoadjuvant or standalone treatment for hepatocellular carcinoma.

Keywords:
hepatocellular carcinomainterventional radiologyradiation segmentectomyradioembolization

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Area of Science:

  • Hepatobiliary Medicine
  • Interventional Radiology
  • Radiation Oncology

Background:

  • Hepatocellular carcinoma (HCC) is a primary liver cancer with limited treatment options.
  • Transarterial radioembolization (TARE) offers targeted internal radiation therapy for liver tumors.
  • Radiation segmentectomy is a precise TARE technique delivering high doses to small liver volumes.

Purpose of the Study:

  • To review the principles and techniques of radiation segmentectomy.
  • To discuss current indications for this liver-directed therapy.
  • To summarize recent outcome data and provide postprocedural management guidelines.

Main Methods:

  • Yttrium-90 (Y-90) transarterial radioembolization is employed.
  • Precise delivery of radiation to a targeted liver segment is achieved.
  • Sparing of surrounding healthy liver parenchyma is a key principle.

Main Results:

  • Radiation segmentectomy achieves high tumoricidal doses with anatomic precision.
  • It is an effective neoadjuvant therapy for liver transplant or resection.
  • It demonstrates efficacy as a standalone treatment for hepatocellular carcinoma.

Conclusions:

  • Radiation segmentectomy is a valuable therapeutic option for HCC.
  • Careful patient selection and precise technique are crucial for optimal outcomes.
  • Further research into its role in multimodal cancer therapy is warranted.