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Updated: Oct 17, 2025

Assessment of Memory Function in Pilocarpine-induced Epileptic Mice
Published on: June 4, 2020
Memory complaints, clinical aspects, and self-esteem in adult people with epilepsy
Glória Maria de Almeida Souza Tedrus1, Laura Annoni Lange2
1Postgraduate Program in Health Sciences, Pontifícia Universidade Católica de Campinas - Campinas, SP, Brazil.
Abstract:
Memory complaints are common in adult people with epilepsy (PWEs). However, the associated clinical aspects are not yet fully understood.
Objective:
This study aims to relate the occurrence of memory complaints in PWEs with clinical aspects and self-esteem.
Methods:
To relate the data obtained from the Memory Complaint Questionnaire (MAC-Q) with clinical aspects, 71 PWEs were assessed using the Rosenberg Self-Esteem Scale (SES), the Mini Mental State Examination (MMSE), and the Brief Cognitive Battery-Edu. These data were compared with 55 individuals in a control group (CG).
Results:
Memory complaints (MAC-Q≥25) were significantly higher in PWEs, when compared with individuals in the CG [35 (49.3%) vs. 15 (27.2%); Student's t-test; p=0.012]. Objective cognitive performance was lower in PWEs. Memory complaints were associated with a lower educational level, the presence of depression, SES, MMSE, incidental memory, and the clock-drawing test scores in PWEs.
Conclusions:
Memory complaints were more frequent in PWEs than in individuals in the CG, and there was a relationship with cognitive deficit, educational level, depression, and low self-esteem.
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