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Effect of chlormethiazole on the hepatic monooxygenase enzyme system
Acta Psychiatrica Scandinavica. Supplementum
|January 1, 1986
Abstract:
Ethanol abuse has been shown to induce hepatic monooxygenase activity. In order to study the effect of chlormethiazole on the hepatic monooxygenase enzyme system, the O-deethylation of 7-ethoxycoumarin was studied. Chlormethiazole was found to inhibit ethanol-induced monooxygenase activity.