Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Vestibular System01:29

The Vestibular System

41.1K
The vestibular system is a set of inner ear structures that provide a sense of balance and spatial orientation. This system is comprised of structures within the labyrinth of the inner ear, including the cochlea and two otolith organs—the utricle and saccule. The labyrinth also contains three semicircular canals—superior, posterior, and horizontal—that are oriented on different planes.
41.1K
Equilibrium and Balance01:15

Equilibrium and Balance

5.2K
The inner ear assumes dual functionalities of auditory perception and equilibrium maintenance. The vestibule is the organ responsible for balance. This organ contains mechanoreceptors, specifically hair cells, endowed with stereocilia, which aid in deciphering information regarding the position and motion of our heads. Two intrinsic components, the utricle and saccule, help perceive head position, while the semicircular canals track head movement. Neurological messages initiated in the...
5.2K
The Cochlea01:13

The Cochlea

47.4K
The cochlea is a coiled structure in the inner ear that contains hair cells—the sensory receptors of the auditory system. Sound waves are transmitted to the cochlea by small bones attached to the eardrum called the ossicles, which vibrate the oval window that leads to the inner ear. This causes fluid in the chambers of the cochlea to move, vibrating the basilar membrane.
47.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

STING signaling in vestibular macrophages underlies Ménière's disease pathogenesis.

Journal of neuroinflammation·2026
Same author

GATA4-Driven Transcription of HtrA1 Promotes Cellular Senescence in Ménière's Disease and Age-Related Audio-Vestibular Dysfunction.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

Brimonidine Therapy for Protection From Noise-Induced Hearing Loss.

Aging cell·2026
Same author

[Surgical treatment of Meniere's disease].

Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery·2026
Same author

A Stress-Neuroendocrine-Myeloid Inflammation Axis Is Associated with the Progression of Ménière's Disease.

Brain, behavior, & immunity - health·2026
Same author

Intranasal Approach of Thermoresponsive Hydrogel Delivering Dexamethasone to the Inner Ear for Treating Hearing Loss.

ACS applied materials & interfaces·2026

Related Experiment Video

Updated: Oct 17, 2025

Using Unidirectional Rotations to Improve Vestibular System Asymmetry in Patients with Vestibular Dysfunction
05:02

Using Unidirectional Rotations to Improve Vestibular System Asymmetry in Patients with Vestibular Dysfunction

Published on: August 30, 2019

7.4K

Objective vestibular function changes in children following cochlear implantation.

Ruijie Wang1,2, Xiuhua Chao1,2, Jianfen Luo1,2

  • 1Department of Otolaryngology-Head and Neck Surgery, Shandong Provincial ENT Hospital, Cheeloo College of Medicine, Shandong University, Jinan, P.R. China.

Journal of Vestibular Research : Equilibrium & Orientation
|October 11, 2021
PubMed
Summary
This summary is machine-generated.

Cochlear implantation (CI) in children can affect vestibular function, particularly the otolith organs. This study evaluated vestibular function pre- and post-CI in children with large vestibular aqueduct syndrome (LVAS) and normal CT scans.

Keywords:
Cochlear implantationLVASchildrenvestibular function

More Related Videos

Systematic Hearing Performance Evaluation Process for Adolescents with Cochlear Implantation at Early Ages
06:04

Systematic Hearing Performance Evaluation Process for Adolescents with Cochlear Implantation at Early Ages

Published on: March 24, 2023

521
Estimating Vestibular Perceptual Thresholds Using a Six-Degree-Of-Freedom Motion Platform
06:31

Estimating Vestibular Perceptual Thresholds Using a Six-Degree-Of-Freedom Motion Platform

Published on: August 4, 2022

3.2K

Related Experiment Videos

Last Updated: Oct 17, 2025

Using Unidirectional Rotations to Improve Vestibular System Asymmetry in Patients with Vestibular Dysfunction
05:02

Using Unidirectional Rotations to Improve Vestibular System Asymmetry in Patients with Vestibular Dysfunction

Published on: August 30, 2019

7.4K
Systematic Hearing Performance Evaluation Process for Adolescents with Cochlear Implantation at Early Ages
06:04

Systematic Hearing Performance Evaluation Process for Adolescents with Cochlear Implantation at Early Ages

Published on: March 24, 2023

521
Estimating Vestibular Perceptual Thresholds Using a Six-Degree-Of-Freedom Motion Platform
06:31

Estimating Vestibular Perceptual Thresholds Using a Six-Degree-Of-Freedom Motion Platform

Published on: August 4, 2022

3.2K

Area of Science:

  • Otolaryngology
  • Neuroscience
  • Pediatrics

Background:

  • Objective vestibular function evaluations in pediatric cochlear implantation (CI) are limited, especially for children with large vestibular aqueduct syndrome (LVAS).
  • Understanding the impact of CI on vestibular function is crucial for managing hearing loss and associated conditions.

Purpose of the Study:

  • To investigate the function of all five vestibular end-organs before and after cochlear implantation in children with LVAS and normal computed tomography (CT) scans.
  • To compare the effects of CI on vestibular function between children with LVAS and those with normal CT.

Main Methods:

  • A retrospective cohort study included 34 children (age 4-17) with bilateral profound sensorineural hearing loss undergoing unilateral CI.
  • Vestibular function was assessed using caloric testing, cervical and ocular vestibular-evoked myogenic potentials (cVEMP, oVEMP), and video head impulse testing (vHIT) pre- and 9 months post-CI.
  • Participants included 18 children with LVAS and 16 with normal CT scans.

Main Results:

  • Vestibular function showed increased overall abnormality rates in cVEMP and oVEMP post-CI (p<0.05), indicating otolith organ dysfunction.
  • Higher deterioration rates were observed in cVEMP (53.3%) and oVEMP (52.0%) after surgery (p<0.05).
  • No significant mean gain changes were found in semicircular canal tests (vHIT), and caloric test hypofunction rates did not significantly change.

Conclusions:

  • Otolith organs are the most affected peripheral vestibular sensors following cochlear implantation in children.
  • The impact of CI on otolith function differs between children with LVAS and those with normal CT.
  • A comprehensive vestibular function test battery is recommended for children undergoing cochlear implantation.