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Clinical Outcomes and Patient Satisfaction After Corneal Neurotization
Leon Rafailov1, Jane S Kim2, Clayton Ellis Wisely2
1Division of Oculoplastic Surgery, Department of Ophthalmology, Duke University Medical Center, Durham, NC.
Cornea
|October 11, 2021
Summary
Corneal neurotization (CN) improves corneal health and sensation, with high patient satisfaction. This procedure offers a safe and effective option for patients with ocular surface issues.
Area of Science:
- Ophthalmology
- Regenerative Medicine
- Corneal Surgery
Background:
- Corneal neurotization (CN) is a surgical technique aimed at restoring corneal nerve function.
- Impaired corneal sensation can lead to ocular surface disease and vision impairment.
Purpose of the Study:
- To assess the clinical outcomes of corneal neurotization (CN).
- To evaluate patient perceptions of postoperative results following CN.
Main Methods:
- Retrospective study of 29 eyes in 28 patients who underwent CN.
- Data included ophthalmic examinations, surgical details, and patient-reported outcomes.
- Statistical analysis included eyes with at least 6 months of follow-up.
Main Results:
- 92% of eyes showed improved ocular surface quality, and 85% healed persistent epithelial defects.
- Patients experienced a median gain of 2.3 cm in corneal sensation.
- High patient satisfaction was reported, with 94% experiencing return of skin sensation and 100% willing to undergo the procedure again.
Conclusions:
- Corneal neurotization (CN) effectively improves corneal health and sensibility.
- The procedure is associated with high patient satisfaction and minimal pain and morbidity.

