Comparative analysis of two optical biometry devices: high wavelength swept source OCT versus partial coherence...

Area of Science:

• Ophthalmology
• Biomedical Optics
• Medical Imaging

Background:

• Accurate biometry is crucial for intraocular lens (IOL) power calculation.
• New multimodal high-resolution swept source optical coherence tomography (SSOCT) devices offer advanced imaging capabilities.
• Comparing SSOCT with established partial coherence interferometry (PCI) biometers is essential for clinical validation.

Purpose of the Study:

• To evaluate the measurement reproducibility of a new SSOCT device.
• To compare SSOCT measurements with a PCI biometer (IOLMaster).
• To assess the impact of measurement differences on IOL power calculations.

Main Methods:

• 152 eyes from 152 subjects underwent measurements using both SSOCT (ANTERION) and PCI (IOLMaster).
• Key parameters measured included anterior surface keratometry (K), anterior chamber depth (ACD), white-to-white (WTW), and axial length (AL).
• IOL power was calculated using five standard vergence formulas based on device-specific K values.

Main Results:

• SSOCT and PCI showed comparable results for simulated keratometry and axial length measurements (P > 0.05).
• A statistically significant difference was found in white-to-white measurements between the two devices (P < 0.0001).
• IOL power calculations differed significantly for SRK/T, Hoffer, and Holladay formulas, but not for the Haigis formula.

Conclusions:

• The ANTERION SSOCT demonstrates good reproducibility for keratometry, AL, ACD, and WTW measurements.
• Discrepancies in WTW measurements and subsequent IOL power calculations highlight the need for formula-specific considerations.
• While SSOCT shows promise, careful evaluation of its impact on IOL power calculation across different formulas is warranted.