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Outcome of Urinary Bladder Dysfunction in Children

Sherif M El-Desoky1,2, Mai Banakhar3, Khalid Khashoggi4

  • 1Department of Pediatrics, King Abdulaziz University, Jeddah, 21589, Saudi Arabia. sherifd68@hotmail.com.

Indian Journal of Pediatrics
|October 11, 2021
PubMed

Insights

Children with bladder dysfunction have an 89% 10-year survival rate. Neurologic bladder (NB) significantly increases mortality risk compared to valve bladder syndrome (VBS).

Area of Science:

  • Pediatric Urology
  • Nephrology
  • Pediatric Surgery

Background:

  • Bladder dysfunction is common in children, with neurologic bladder (NB), dysfunctional voiding syndrome (DVS), and valve bladder syndrome (VBS) as frequent causes.
  • Understanding long-term outcomes and associated morbidities is crucial for managing pediatric bladder dysfunction.

Purpose of the Study:

  • To determine the 10-year survival rate in children with bladder dysfunction.
  • To identify factors influencing survival and morbidity, including etiology, GFR, and age at presentation.

Main Methods:

  • A retrospective study included 199 children with bladder dysfunction (60 VBS, 75 DVS, 64 NB).
  • Data analyzed included 10-year survival rates, morbidities, baseline GFR, and age at presentation.

Main Results:

  • The overall 10-year survival rate was 89%.
  • Mortality was 11 times higher in NB patients compared to VBS patients (p=0.02).
  • GFR < 15 mL/min/1.73 m² increased mortality sixfold (p=0.007), and late presentation (>5 years) increased mortality/RRT risk fivefold (p=0.013).

Conclusions:

  • Etiology of bladder dysfunction, baseline GFR, and age at presentation are significant predictors of survival and morbidity in children.
  • Early diagnosis and intervention are critical for improving long-term outcomes in pediatric bladder dysfunction.

Keywords:
Dysfunctional voiding syndromeNeurogenic bladderPost valve bladder

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