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Related Concept Videos

Disorders of the Autonomic Nervous System01:18

Disorders of the Autonomic Nervous System

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The autonomic nervous system (ANS) is an intricate network of nerves that controls functions such as the regulation of heart rate, digestion, and blood pressure regulation. When this system malfunctions, it can lead to various disorders that affect multiple bodily functions. One common feature of many autonomic disorders is the involvement of smooth blood vessels, which play a crucial role in regulating blood flow throughout the body.
Raynaud's disease, also known as Raynaud's...
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Aortic Regurgitation IV: Nursing Management01:17

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A nurse managing a patient with aortic regurgitation begins with a comprehensive assessment, including a review of the patient's medical history, family history, and lifestyle factors. During the cardiac examination, the nurse listens for heart sounds and checks for signs of valve abnormalities. The nurse also observes for symptoms such as dyspnea, orthopnea, and paroxysmal nocturnal dyspnea and assesses the patient's endurance and daily activity tolerance.Based on the findings, the nurse...
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Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

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Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
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Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
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Impaired autonomic function after incomplete revascularisation.

Richard Armstrong1, Peter Wheen2, Lisa Brandon2

  • 1Cardiology, Belfast Health and Social Care Trust, Belfast, UK richarm88@gmail.com.

Open Heart
|October 12, 2021
PubMed
Summary
This summary is machine-generated.

Incomplete cardiac revascularisation (ICR) is linked to poorer autonomic function, specifically heart rate recovery time (HRR10-20). This finding may help identify patients at higher mortality risk after procedures.

Keywords:
atherosclerosiscoronary stenosispercutaneous coronary interventiontranslational medical research

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Area of Science:

  • Cardiology
  • Autonomic Nervous System Function
  • Cardiovascular Physiology

Background:

  • Incomplete cardiac revascularisation (ICR), indicated by a high residual SYNTAX score (rSs), is associated with increased 5-year mortality.
  • Impaired autonomic function, assessed by heart rate recovery time (HRR10-20) after an active stand, is linked to higher all-cause mortality in the general population.

Purpose of the Study:

  • To investigate the hypothesis that ICR is associated with impaired autonomic function, specifically measured by HRR10-20.

Main Methods:

  • Consecutive patients undergoing percutaneous coronary revascularisation were enrolled after informed consent.
  • Heart rate, blood pressure, and ECG were recorded during an active stand to determine HRR10-20.
  • Patients were categorized into complete revascularisation (CR, rSs=0) and ICR (rSs>0) groups.

Main Results:

  • A total of 53 patients (37 CR, 16 ICR) were analyzed. The mean rSs in the ICR group was 9.4.
  • HRR10-20 was significantly impaired in the ICR group (-3±0.60) compared to the CR group (-6.56±0.52) (p<0.0001).
  • A strong correlation (Pearson's r=0.529, p<0.0001) was found between completeness of revascularisation and HRR10-20.

Conclusions:

  • The study confirms a significant correlation between ICR and impaired autonomic function, as indicated by heart rate recovery speed.
  • Assessing autonomic dysfunction in patients with ICR may serve as a valuable tool for identifying individuals at increased risk of mortality.