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Acute Extrapyramidal Side Effects from Smoked Haloperidol.

Angeline Pham¹, Joo-Young Lee¹, Christopher W T Miller¹

¹Department of Psychiatry, University of Maryland Medical Center, USA.

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Summary

This summary is machine-generated.

This case report details the first instance of haloperidol misuse via smoking, combined with marijuana. The patient experienced acute dystonia, highlighting risks of unconventional antipsychotic use.

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Area of Science:

Psychiatry
Pharmacology

Background:

Haloperidol, a typical antipsychotic, is prescribed for psychotic disorders.
High-dose haloperidol increases the risk of extrapyramidal symptoms (EPS).
Limited literature exists on haloperidol misuse.

Observation:

A patient with schizophrenia misused haloperidol by smoking it with marijuana.
Following consumption, the patient presented with suicidal ideation, psychosis, and acute dystonia.
Dystonia resolved rapidly after diphenhydramine administration in the emergency department.

Findings:

This is the first reported case of haloperidol misuse through smoking.
Concurrent use of marijuana with haloperidol may precipitate acute dystonic reactions.

Implications:

Clinicians must consider unconventional routes of prescribed antipsychotic misuse.
Awareness of combined substance use is crucial for managing adverse events.
This case underscores the importance of patient education on proper medication use.