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Updated: Oct 17, 2025

The Synthesis, Characterization and Reactivity of a Series of Ruthenium N-triphosPh Complexes
Published on: April 10, 2015
A Free Radical Cyclization Catalyzed by Ruthenium Hydride Species
Rira Kim1, Kuktae Kwon1, Hee-Yoon Lee1
1Department of Chemistry, Korea Advanced Institute of Science & Technology (KAIST), 134141, 291 Daehak Ro, Yuseong, Daejeon, Korea.
Abstract:
A photolytically generated ruthenium hydride species catalyzing a free radical cyclization reaction was developed. As the new methodology ensures reproducibility of the free radical reaction of trialkyltin hydrides and a fast hydrogen transfer to the radical intermediates, the methodology provides fast quenching of radical intermediates and thus suppresses rearrangement of radical intermediates before the hydride quench. By offering new reactivity and selectivity to the trialkyltin hydride mediated free radical cyclization reactions, the methodology will find wide range of applications in organic synthesis.
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