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Published on: April 11, 2019
Evaluation of Pupillometric Parameters in Patients with COVID-19
Yücel Öztürk1, Merve Beyza Yıldız1, Rüveyde Bolaç1
1Haydarpaşa Numune Training and Research Hospital, Department of Ophthalmology, University of Health Sciences, Istanbul, Turkey.
Purpose:
To investigate the pupillary diameter and pupillary light response in patients who have recovered from the COVID-19.
Methods:
Thirty two eyes of 32 patients with a history of COVID-19 in the last two months and 32 eyes of 32 age and sex-matched healthy controls were included in this prospective study. All patients had neurological symptoms. Dynamic and static pupillometry measurements were performed with the Sirius (CSO, Italy) corneal topography device.
Results:
Patients with COVID-19 had higher mean scotopic, mesopic, and photopic pupil diameters compared to the controls (p = .01, p = .04, p = .02, respectively). In dynamic pupillometry analysis, 0th, 2th, 8th and 16th second pupil diameter measurements were higher in COVID-19 patients (p = .02, p = .04, p = .04, p = .04, respectively). There were no differences in the average speed of pupillary dilatation (p > .05).
Conclusion:
Our findings suggest that the pupillary response, an indicator of autonomic nervous system activity, may be affected in COVID-19 patients with neurological symptoms.
