Related Experiment Video
Updated: Oct 17, 2025
09:48
Fiber Optic Distributed Sensors for High-resolution Temperature Field Mapping
Published on: November 7, 2016
12.2K
Overview and emerging trends in optical fiber aptasensing
Médéric Loyez1, Maria C DeRosa2, Christophe Caucheteur3
1Proteomics and Microbiology Department, University of Mons, Avenue du Champ de Mars 6, 7000, Mons, Belgium; Electromagnetism and Telecommunication Department, University of Mons, Bld. Dolez 31, 7000, Mons, Belgium.
Biosensors & Bioelectronics
|October 12, 2021
Summary
Aptamer-based optical fiber biosensors offer superior specificity and sensitivity for detecting biomarkers. This review highlights recent advances and future challenges in this key technology for medical, food, and environmental applications.
Area of Science:
- Biomedical Engineering
- Nanotechnology
- Analytical Chemistry
Background:
- Optical fiber biosensors are increasingly vital for detecting low concentrations of biomarkers in small volumes.
- Aptamer-based sensors demonstrate exceptional ease of production, specificity, and sensitivity.
- DNA aptamers serve as stable bioreceptors for diverse applications like medical diagnostics and environmental monitoring.
Purpose of the Study:
- To review recent advancements in aptamer-based optical fiber biosensors.
- To analyze various fiber-optic structures and immobilization strategies for aptamer receptors.
- To discuss current sensor features, challenges, and future prospects.
Main Methods:
- Comprehensive literature analysis of aptamer-based optical fiber biosensors.
- Examination of different fiber-optic sensing platforms and biochemical immobilization techniques.
- Evaluation of biochemical and optical parameters influencing sensor performance.
Main Results:
- Aptamers provide high specificity and sensitivity in optical fiber biosensing.
- Diverse immobilization strategies enhance aptamer stability and performance.
- Recent advances show promise for medical, food safety, and environmental monitoring.
Conclusions:
- Aptamer-based optical fiber biosensors represent a significant technological advancement.
- Further research is needed to address challenges in sensor design and application.
- This field holds substantial promise for future innovations in biosensing.
