11q23 involvement in a complex insertion (10; 11) in acute monocytic leukemia

A variant insertion (10p; 11q) preceded by a paracentric inversion of the long arm of chromosome 11, inv(11)(q12q23), has been found in a patient with ANLL-M5a. The association of 11q abnormalities involving the breakpoint 11q23 with acute monocytic leukemia is confirmed.