Related Experiment Video
Updated: Oct 17, 2025

Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles
Published on: January 26, 2024
Gestational Bell's Palsy Is Associated with Higher Blood Pressure during Late Pregnancy and Lower Birth Weight: A
Sumonthip Leelawai1, Chitkasaem Suwanrath2, Nannapat Pruphetkaew3
1Division of Neurology, Department of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand.
Insights
Gestational Bell's palsy (GBP) may be linked to higher maternal blood pressure but not other late obstetric complications. Newborns of mothers with GBP had significantly lower birth weights, suggesting potential neonatal health impacts.
Area of Science:
- Obstetrics and Gynecology
- Neurology
- Neonatology
Background:
- The relationship between gestational Bell's palsy (GBP) and late obstetric complications (LOCs) like preeclampsia and gestational diabetes is not well-defined.
- Evaluating neonatal outcomes in pregnancies affected by GBP is crucial for understanding potential risks.
Purpose of the Study:
- To investigate the associations between gestational Bell's palsy and specific late obstetric complications.
- To compare the neonatal health indices of newborns born to mothers with and without gestational Bell's palsy.
Main Methods:
- A retrospective case-control study design was employed, matching 8 cases of gestational Bell's palsy with 40 controls.
- Data were collected from Songklanagarind Hospital between 2006 and 2016.
- Bivariate analysis was used to assess associations and compare neonatal outcomes.
Main Results:
- While no definitive associations were found between GBP and preeclampsia, eclampsia, gestational hypertension, or gestational diabetes due to limited statistical power, GBP cases exhibited higher systolic and diastolic blood pressures.
- Newborns of mothers with gestational Bell's palsy showed a statistically significant lower mean birth weight compared to controls.
- The study identified higher maternal blood pressures and lower neonatal birth weights in the context of gestational Bell's palsy.
Conclusions:
- The association between gestational Bell's palsy and late obstetric complications remains inconclusive due to the small number of cases.
- A significantly lower mean birth weight in newborns of mothers with gestational Bell's palsy suggests a potential impact on neonatal health.
- Further research with larger sample sizes is warranted to clarify the relationship between GBP and LOCs and their impact on neonatal outcomes.
Abstract:
The associations between gestational Bell's palsy (GBP) and late obstetric complications (LOCs), i.e., preeclampsia (PE), eclampsia (EC), gestational hypertension (GHT), and gestational diabetes mellitus (GDM) remain unclear. This study aimed to evaluate these associations and the neonatal health of the newborns born from pregnant women with and without GBP. A retrospective 1:5 case-control study matching exact maternal age and gravidity between pregnant women with and without GBP in Songklanagarind Hospital from 2006 to 2016 was conducted. The associations between GBP and PE, EC, GHT, and GDM, as well as comparison of the newborns' health indices were analyzed by bivariate analysis (p < 0.05). Eight GBP cases out of 8,756 pregnant women were recruited. Six GBP cases were first or second gravid. GBP occurred during the third trimester in five cases. Except for higher median systolic blood pressure (125 (114.2, 127.5) vs. (110 (107.0, 116.0), p = 0.045) and diastolic blood pressures (77 (73.0, 80.8) vs. 70 (65.0, 73.2), p = 0.021) in the GBP cases, associations between GBP and all LOCs could not be concluded due to the lack of power. However, a significantly lower mean birth weight in the newborns of GBP mothers was found (2672.2 (744.0) vs. 3154.8 (464.7), p = 0.016) with statistically significant power. Except for the higher blood pressures and lower birth weights of the newborns of GBP mothers, an association between GBP and LOCs remains inconclusive.
Related Concept Videos
Mitral Valve Prolapse III: Nursing Management
Factors affecting Blood pressure
Physiological Factors:
Pre-Procedural Guidelines for Assessing Blood Pressure
Special considerations while measuring blood pressure
Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.
Measurement of Blood Pressure
Pathophysiology of Diabetes
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...

