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Venous thromboembolism in patients with COVID-19 infection: risk factors, prevention, and management

Natasha Ahuja1, Jasmine Bhinder1, Jessica Nguyen1

  • 1Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo General Medical Center/Kaleida Health, 100 High Street, B7, Buffalo, NY, 14203.

Seminars in Vascular Surgery
|October 13, 2021
PubMed

Insights

COVID-19 infections can lead to serious venous thromboembolic complications. This review covers COVID-19

Area of Science:

  • Hematology, Infectious Diseases, Critical Care Medicine

Background:

  • COVID-19 is associated with a significant risk of venous thromboembolic events (VTE).
  • Understanding the pathophysiology and risk factors for VTE in COVID-19 is crucial for patient management.

Purpose of the Study:

  • To provide a comprehensive summary of current knowledge on venous thromboembolism in COVID-19.
  • To outline pathophysiology, risk factors, incidence, prophylaxis, and treatment of VTE in COVID-19 patients.

Main Methods:

  • Review of current literature and data on venous thromboembolic complications in COVID-19.
  • Synthesis of information on pathophysiology, risk factors, hematologic markers, incidence, timing, atypical presentations, and management strategies.

Main Results:

  • COVID-19 patients exhibit unique risk factors and hematologic profiles associated with VTE.
  • Specific incidence and timing patterns of venous events in COVID-19 have been observed.
  • Atypical presentations of VTE can occur in the context of COVID-19.

Conclusions:

  • Venous thromboembolism is a critical concern in COVID-19 management.
  • Evidence-based prophylaxis and therapeutic recommendations are essential for mitigating VTE risk.
  • Ongoing research is vital as understanding of COVID-19-associated VTE continues to evolve.

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