Current evidence for transcarotid artery stenting with flow reversal as the preferred carotid artery stenting
Patric Liang1, Marc L Schermerhorn1
1Department of Surgery, Division of Vascular and Endovascular Surgery, Beth Israel Deaconess Medical Center and Harvard Medical School, 110 Francis Street, Suite 5B, Boston, MA 02215.
Insights
Transcarotid artery revascularization (TCAR) offers improved stroke and death outcomes compared to the transfemoral approach for carotid artery stenting. TCAR is increasingly preferred due to its neuroprotection system, reducing embolic risks.
Area of Science:
- Vascular Surgery
- Interventional Cardiology
- Neurology
Background:
- Transfemoral carotid artery stenting (TF-CAS) is a minimally invasive treatment for carotid atherosclerotic disease.
- TF-CAS outcomes in symptomatic or high-risk patients have not matched endarterectomy.
- Embolic risk is a significant concern with the transfemoral approach.
Purpose of the Study:
- To evaluate Transcarotid artery revascularization (TCAR) as an alternative to TF-CAS.
- To highlight the neuroprotection system of TCAR in reducing embolic events.
- To compare the benefits of TCAR versus TF-CAS.
Main Methods:
- TCAR utilizes a flow reversal neuroprotection system.
- This system is designed to mitigate embolic risks inherent in TF-CAS.
- Ongoing research and accumulating evidence support TCAR's efficacy.
Main Results:
- TCAR demonstrates reduced stroke or death benefits compared to the transfemoral approach.
- The flow reversal system in TCAR aims to minimize embolic complications.
- While randomized trials are pending, clinical adoption is growing.
Conclusions:
- TCAR is emerging as a preferred method for carotid artery stenting.
- The procedure offers potential advantages in reducing stroke and death.
- Further randomized trials are needed to confirm TCAR's superiority over TF-CAS.
Abstract:
Although the transfemoral approach to carotid artery stenting offers a minimally invasive method for treatment of carotid atherosclerotic disease, this technique for carotid revascularization has unfortunately not led to equivalent overall outcomes of stroke or death compared with endarterectomy in symptomatic or high-risk patients. Transcarotid artery revascularization (TCAR) with a flow reversal neuroprotection system was designed to reduce the embolic risk associated with the transfemoral approach, but randomized trials have yet to be published comparing transfemoral carotid artery stenting with TCAR. Regardless, many surgeons and interventionalists have already adopted TCAR as the preferred modality for carotid artery stenting, given the accumulating evidence supporting the reduced stroke or death benefits of TCAR over the transfemoral approach.
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