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Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
Published on: November 10, 2023
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Hantavirus Disease and COVID-19
Allison K Joyce1, Tarrah T Oliver2, Aaron D Kofman3
1National Center for Emerging and Zoonotic Infectious Diseases, CDC, Atlanta, GA, USA.
American Journal of Clinical Pathology
|October 13, 2021
Summary
The hantavirus 5-point screen effectively distinguishes hantavirus cardiopulmonary syndrome (HCPS) from COVID-19. This rapid screening tool aids in differentiating these critical respiratory illnesses, especially in endemic areas.
Area of Science:
- Infectious Diseases
- Hematology
- Public Health
Background:
- Hantavirus cardiopulmonary syndrome (HCPS) severely affects the Navajo Nation, presenting symptoms similar to COVID-19.
- Distinguishing between HCPS and COVID-19 is crucial due to differing disease progression and outcomes.
Purpose of the Study:
- To evaluate the efficacy of the "hantavirus 5-point screen" in differentiating HCPS from COVID-19.
- To assess if hematopathologic criteria in peripheral blood smears can distinguish between these two respiratory diseases.
Main Methods:
- Peripheral blood smears from 139 COVID-19 patients were analyzed using the hantavirus 5-point screen.
- Patients were treated at Tséhootsooí Medical Center and Emory University hospitals.
Main Results:
- 98% of COVID-19 patients scored 3/5 or below, indicating low suspicion for HCPS.
- Thrombocytopenia, a key HCPS indicator, was mild and stable in COVID-19 patients.
Conclusions:
- The hantavirus 5-point screen is a valuable rapid tool for identifying potential HCPS cases.
- This screening method can help differentiate early HCPS from COVID-19 in regions where hantavirus is endemic.
Keywords:
COVID-19HantavirusHantavirus cardiopulmonary syndromePeripheral blood smearRapid screenThrombocytopeniaMore Related Videos
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